日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Lopinavir Derivative as Potent P-gp Inhibitor Enables Delivery through HPMA Copolymer Conjugates and Overcoming Tumor Chemoresistance to Conventional Cytostatic Drugs

洛匹那韦衍生物作为强效P-gp抑制剂，可通过HPMA共聚物偶联物递送，克服肿瘤对传统细胞抑制剂的化疗耐药性。

期刊:Biomacromolecules
影响因子:5.4
doi:10.1021/acs.biomac.5c02097
Starenko, Daniil; Kostka, Libor; Behalova, Katerina; Kotrchova, Lenka; Subr, Vladimir; Kovarova, Jirina; Roubalova, Radka; Sirova, Milada; Etrych, Tomas; Kovar, Marek
细胞生物学
肿瘤
肿瘤免疫
发表日期：2026
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TIMED-Design: flexible and accessible protein sequence design with convolutional neural networks

TIMED-Design：利用卷积神经网络实现灵活便捷的蛋白质序列设计

期刊:Protein Engineering Design & Selection
影响因子:3.4
doi:10.1093/protein/gzae002
Castorina, Leonardo V; Ünal, Suleyman Mert; Subr, Kartic; Wood, Christopher W
TIM
发表日期：2024
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Anti-Extra Domain B Splice Variant of Fibronectin Antibody-Drug Conjugate Eliminates Tumors with Enhanced Efficacy When Combined with Checkpoint Blockade

抗额外结构域 B 剪接变体纤连蛋白抗体-药物偶联物与检查点阻断剂联合使用可增强肿瘤消除效果

期刊:Molecular Cancer Therapeutics
影响因子:5.3
doi:10.1158/1535-7163.MCT-22-0099
Andrea T Hooper, Kimberly Marquette, Chao-Pei Betty Chang, Jonathon Golas, Sadhana Jain, My-Hanh Lam, Magali Guffroy, Mauricio Leal, Hadi Falahatpisheh, Divya Mathur, Ting Chen, Kerry Kelleher, Kiran Khandke, Elwira Muszynska, Frank Loganzo, Edward Rosfjord, Judy Lucas, Zhengyan Kan, Chakrapani Subr
肿瘤
Checkpoint
发表日期：2022
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Comprehensive evaluation of electrophysiological and 3D structural features of human atrial myocardium with insights on atrial fibrillation maintenance mechanisms

对人类心房肌的电生理和三维结构特征进行全面评估，并深入探讨心房颤动的维持机制。

期刊:Journal of Molecular and Cellular Cardiology
影响因子:4.7
doi:10.1016/j.yjmcc.2020.10.012
Mikhailov, Aleksei V; Kalyanasundaram, Anuradha; Li, Ning; Scott, Shane S; Artiga, Esthela J; Subr, Megan M; Zhao, Jichao; Hansen, Brian J; Hummel, John D; Fedorov, Vadim V
发表日期：2021
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Lactate Elicits ER-Mitochondrial Mg2+ Dynamics to Integrate Cellular Metabolism

乳酸引发内质网线粒体 Mg2+ 动力学以整合细胞代谢

期刊:Cell
影响因子:45.5
doi:10.1016/j.cell.2020.08.049
Cassidy C Daw, Karthik Ramachandran, Benjamin T Enslow, Soumya Maity, Brian Bursic, Matthew J Novello, Cherubina S Rubannelsonkumar, Ayah H Mashal, Joel Ravichandran, Terry M Bakewell, Weiwei Wang, Kang Li, Travis R Madaris, Christopher E Shannon, Luke Norton, Soundarya Kandala, Jeffrey Caplan, Subr
代谢
其它细胞
发表日期：2020
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Unmasking Arrhythmogenic Hubs of Reentry Driving Persistent Atrial Fibrillation for Patient-Specific Treatment

揭示导致持续性房颤的折返性心律失常中心，以实现个体化治疗

期刊:Journal of the American Heart Association
影响因子:5.3
doi:10.1161/JAHA.120.017789
Hansen, Brian J; Zhao, Jichao; Helfrich, Katelynn M; Li, Ning; Iancau, Alexander; Zolotarev, Alexander M; Zakharkin, Stanislav O; Kalyanasundaram, Anuradha; Subr, Megan; Dastagir, Nawshin; Sharma, Roshan; Artiga, Esthela J; Salgia, Nicholas; Houmsse, Mustafa M; Kahaly, Omar; Janssen, Paul M L; Mohler, Peter J; Mokadam, Nahush A; Whitson, Bryan A; Afzal, Muhammad R; Simonetti, Orlando P; Hummel, John D; Fedorov, Vadim V
发表日期：2020
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Augmentation of EPR Effect and Efficacy of Anticancer Nanomedicine by Carbon Monoxide Generating Agents

一氧化碳发生剂增强EPR效应及抗癌纳米药物疗效

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics11070343
Fang, Jun; Islam, Rayhanul; Islam, Waliul; Yin, Hongzhuan; Subr, Vladimir; Etrych, Tomas; Ulbrich, Karel; Maeda, Hiroshi
肿瘤
肿瘤免疫
发表日期：2019
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Photodynamic therapy and imaging based on tumor-targeted nanoprobe, polymer-conjugated zinc protoporphyrin

基于肿瘤靶向纳米探针——聚合物偶联锌原卟啉的光动力疗法和成像

期刊:Future Science OA
影响因子:2.1
doi:10.4155/fso.15.2
Fang, Jun; Liao, Long; Yin, Hongzhuan; Nakamura, Hideaki; Subr, Vladimir; Ulbrich, Karel; Maeda, Hiroshi
肿瘤
肿瘤免疫
发表日期：2015
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Traceless bioresponsive shielding of adenovirus hexon with HPMA copolymers maintains transduction capacity in vitro and in vivo

腺病毒六邻体与 HPMA 共聚物的无痕生物响应屏蔽保持了体外和体内的转导能力

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0082716
Jan-Michael Prill, Vladimír Subr, Noemi Pasquarelli, Tatjana Engler, Andrea Hoffmeister, Stefan Kochanek, Karel Ulbrich, Florian Kreppel
免疫
微生物学
发表日期：2014
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In Vivo Nanotoxicity Testing using the Zebrafish Embryo Assay

利用斑马鱼胚胎试验进行体内纳米毒性测试

期刊:Journal of Materials Chemistry B
影响因子:5.7
doi:10.1039/C3TB20528B
Rizzo, Larissa Y; Golombek, Susanne K; Mertens, Marianne E; Pan, Yu; Laaf, Dominic; Broda, Janine; Jayapaul, Jabadurai; Möckel, Diana; Subr, Vladimir; Hennink, Wim E; Storm, Gert; Simon, Ulrich; Jahnen-Dechent, Willi; Kiessling, Fabian; Lammers, Twan
毒理研究
发表日期：2013
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