日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Effects of a Combined Dietary and Physical Activity Intervention on Bone Density, Lean Mass and Fat Mass in Adults: The GOTO Trial

饮食和体育活动联合干预对成人骨密度、瘦体重和脂肪量的影响：GOTO试验

期刊:Journal of Cachexia Sarcopenia and Muscle
影响因子:9.1
doi:10.1002/jcsm.70226
Bogaards, F A; Groenendijk, Inge; Gehrmann, Thies; Beekman, Marian; Lakenberg, Nico; Suchiman, H Eka D; de Groot, Lisette C P G M; Reinders, Marcel J T; Slagboom, P Eline
发表日期：2026
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Therapeutic efficacy of extracellular vesicles from hiPSC-derived MSCs in serum-containing and xeno-free media for osteoarthritis treatment.

hiPSC衍生的MSC细胞外囊泡在含血清和无异种成分培养基中治疗骨关节炎的疗效。

期刊:Stem Cell Research & Therapy
影响因子:7.3
doi:10.1186/s13287-025-04890-6
Sayedipour S Sana, Nikkels Jelle, Tertel Tobias, Suchiman Helena E D, Koedam Marijke, Balbi Matilde, Shaw Georgina, Cruz Luis J, van der Eerden Bram C J, van der Weerd Louise, Gentili Chiara, Giebel Bernd, Murphy Josephine Mary, Meulenbelt Ingrid, Ramos Yolande F M
关节炎
细胞生物学
囊泡
发表日期：2026
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Tissue-specific methylomic responses to a lifestyle intervention in older adults associate with metabolic and physiological health improvements

老年人生活方式干预引起的组织特异性甲基化组学反应与代谢和生理健康改善相关。

期刊:Aging Cell
影响因子:7.1
doi:10.1111/acel.14431
Sinke, Lucy; Beekman, Marian; Raz, Yotam; Gehrmann, Thies; Moustakas, Ioannis; Boulinguiez, Alexis; Lakenberg, Nico; Suchiman, Eka; Bogaards, Fatih A; Bizzarri, Daniele; van den Akker, Erik B; Waldenberger, Melanie; Butler-Browne, Gillian; Trollet, Capucine; de Groot, C P G M; Heijmans, Bastiaan T; Slagboom, P Eline
表观遗传
代谢
发表日期：2025
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Rare longevity-associated variants, including a reduced-function mutation in cGAS, identified in multigenerational long-lived families

在多代长寿家族中发现了罕见的与长寿相关的变异，包括cGAS基因中的功能降低突变。

期刊:
影响因子:
doi:10.64898/2025.12.04.689698
Putter, Pasquale C; Guan, Di; Gehrmann, Thies; Kolbe, Daniel; Yang, Jiping; Han, HyeRim; Kim, Seungsoo; Lakenberg, Nico; Suchiman, H Eka D; Trompet, Stella; Liu, Georg C; Ballhysa, Eugen; Antebi, Adam; van den Berg, Niels M A; Nebel, Almut; Beekman, Marian; Suh, Yousin; Slagboom, P Eline; Deelen, Joris
发表日期：2025
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Secondary integrated analysis of multi-tissue transcriptomic responses to a combined lifestyle intervention in older adults from the GOTO nonrandomized trial

对GOTO非随机试验中老年人多种组织转录组对综合生活方式干预的反应进行二次整合分析

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-024-50693-3
Bogaards, F A; Gehrmann, T; Beekman, M; Lakenberg, N; Suchiman, H E D; de Groot, C P G M; Reinders, M J T; Slagboom, P E
发表日期：2024
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Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis

关节软骨和软骨下骨中的等位基因表达失衡细化了骨关节炎的全基因组关联信号

期刊:Rheumatology
影响因子:4.4
doi:10.1093/rheumatology/keac498
Coutinho de Almeida, Rodrigo; Tuerlings, Margo; Ramos, Yolande; Den Hollander, Wouter; Suchiman, Eka; Lakenberg, Nico; Nelissen, Rob G H H; Mei, Hailiang; Meulenbelt, Ingrid
信号转导
关节炎
发表日期：2023
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Identification and functional characterization of imbalanced osteoarthritis-associated fibronectin splice variants

不平衡骨关节炎相关纤连蛋白剪接变体的鉴定和功能表征

期刊:Rheumatology
影响因子:
doi:10.1093/rheumatology/keac272
Marcella van Hoolwerff, Margo Tuerlings, Imke J L Wijnen, H Eka D Suchiman, Davy Cats, Hailiang Mei, Rob G H H Nelissen, Henrike M J van der Linden-van der Zwaag, Yolande F M Ramos, Rodrigo Coutinho de Almeida, Ingrid Meulenbelt
免疫
关节炎
发表日期：2023
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Characterizing the secretome of licensed hiPSC-derived MSCs

鉴定已获许可的 hiPSC 衍生 MSC 的分泌蛋白组

期刊:Stem Cell Research
影响因子:7.1
doi:10.1186/s13287-022-03117-2
Yolande F M Ramos, Tobias Tertel, Georgina Shaw, Simon Staubach, Rodrigo Coutinho de Almeida, Eka Suchiman, Thomas B Kuipers, Hailiang Mei, Frank Barry, Mary Murphy, Bernd Giebel, Ingrid Meulenbelt
多发性硬化症
发表日期：2022
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The role of TNFRSF11B in development of osteoarthritic cartilage

TNFRSF11B 在骨关节炎软骨发育中的作用

期刊:Rheumatology
影响因子:
doi:10.1093/rheumatology/keab440
Alejandro Rodríguez Ruiz, Margo Tuerlings, Ankita Das, Rodrigo Coutinho de Almeida, H Eka D Suchiman, Rob G H H Nelissen, Yolande F M Ramos, Ingrid Meulenbelt
免疫
关节炎
发表日期：2022
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High-impact FN1 mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II

高影响的 FN1 突变会降低软骨形成潜力，并通过降低与 II 型胶原蛋白的结合来影响软骨沉积

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.abg8583
Marcella van Hoolwerff, Alejandro Rodríguez Ruiz, Marga Bouma, H Eka D Suchiman, Roman I Koning, Carolina R Jost, Aat A Mulder, Christian Freund, Farshid Guilak, Yolande F M Ramos, Ingrid Meulenbelt
信号转导
发表日期：2021
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