Upregulation of the EGFR/MEK1/MAPK1/2 signaling axis as a mechanism of resistance to antiestrogen‑induced BimEL dependent apoptosis in ER+ breast cancer cells
EGFR/MEK1/MAPK1/2信号通路的上调是ER+乳腺癌细胞抵抗抗雌激素诱导的BimEL依赖性细胞凋亡的机制之一。
期刊:International Journal of Oncology
影响因子:4.5
doi:10.3892/ijo.2022.5468
Mackenzie L Hagan,Suchreet Mander,Carol Joseph,Michael McGrath,Amanda Barrett,Allison Lewis,William D Hill,Darren Browning,Meghan E McGee-Lawrence,Haifeng Cai,Kebin Liu,John T Barrett,David A Gewirtz,Muthusamy Thangaraju,Patricia V Schoenlein
乳腺癌
信号转导
细胞生物学
信号转导
肿瘤
表观遗传
EGF
EGFR
MEK1
Apoptosis
凋亡
