日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pathogenic variants at the N-terminal arginine residue 44 disrupt human GABA transporter 1 function: insights from Drosophila epilepsy models

N端精氨酸残基44处的致病性变异会破坏人类GABA转运蛋白1的功能:来自果蝇癫痫模型的启示

Nikita Shah # ,Ameya Sanjay Kasture # ,Vasylyna Kovalchuk ,Lara Bjeletic ,Thomas Hummel ,Harald H Sitte ,Sonja Sucic

Rescue of Epilepsy-Associated Mutations of the Highly Conserved Glycine Residue 443 in the Human GABA Transporter 1

拯救人类 GABA 转运蛋白 1 中高度保守的甘氨酸残基 443 的癫痫相关突变

Nikita Shah ,Vasylyna Kovalchuk ,Rocco Zerlotti ,Kim Cole ,Andre Bazzone ,Harald H Sitte ,Thomas Hummel ,Ameya S Kasture ,Sonja Sucic

Probing binding and occlusion of substrate in the human creatine transporter-1 by computation and mutagenesis

通过计算和诱变探测人类肌酸转运蛋白-1 中底物的结合和阻断

Amy Clarke, Clemens V Farr, Ali El-Kasaby, Daniel Szöllősi, Michael Freissmuth, Sonja Sucic, Thomas Stockner

The impact of astrocytic NF-κB on healthy and Alzheimer's disease brains

星形胶质细胞 NF-κB 对健康大脑和阿尔茨海默病大脑的影响

Jong Huat, Tee; Camats-Perna, Judith; Newcombe, Estella A; Onraet, Tessa; Campbell, Daniel; Sucic, Josiah T; Martini, Alessandra; Forner, Stefânia; Mirzaei, Mehdi; Poon, Wayne; LaFerla, Frank M; Medeiros, Rodrigo

A mechanism of uncompetitive inhibition of the serotonin transporter

血清素转运蛋白的非竞争性抑制机制

Shreyas Bhat, Ali El-Kasaby, Ameya Kasture, Danila Boytsov, Julian B Reichelt, Thomas Hummel, Sonja Sucic, Christian Pifl, Michael Freissmuth, Walter Sandtner

Drosophila melanogaster as a model for unraveling unique molecular features of epilepsy elicited by human GABA transporter 1 variants

以果蝇为模型,揭示人类 GABA 转运蛋白 1 变体引起的癫痫的独特分子特征

Ameya S Kasture, Florian P Fischer, Lisa Kunert, Melanie L Burger, Alexander C Burgstaller, Ali El-Kasaby, Thomas Hummel, Sonja Sucic

Rescue of Misfolded Organic Cation Transporter 3 Variants

挽救错误折叠的有机阳离子转运体 3 变体

Thomas J F Angenoorth, Julian Maier, Stevan Stankovic, Shreyas Bhat, Sonja Sucic, Michael Freissmuth, Harald H Sitte, Jae-Won Yang

Cooperative Binding of Substrate and Ions Drives Forward Cycling of the Human Creatine Transporter-1

底物和离子的协同结合推动人类肌酸转运蛋白-1的正向循环

Clemens V Farr, Ali El-Kasaby, Fatma A Erdem, Sonja Sucic, Michael Freissmuth, Walter Sandtner

Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits

神经递质转运蛋白疾病变异的功能和生化后果:特别关注折叠和转运缺陷

Bhat, Shreyas; El-Kasaby, Ali; Freissmuth, Michael; Sucic, Sonja

Constitutive Endocytosis of the Neuronal Glutamate Transporter Excitatory Amino Acid Transporter-3 Requires ARFGAP1

神经元谷氨酸转运体兴奋性氨基酸转运体-3 的组成性内吞作用需要 ARFGAP1

Kusumika Saha, Jae-Won Yang, Tina Hofmaier, SanthoshKannan Venkatesan, Thomas Steinkellner, Oliver Kudlacek, Sonja Sucic, Michael Freissmuth, Harald H Sitte