日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

The allure of targets for novel drugs

新型药物靶点的吸引力

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d3md00621b
Suckling, Colin J
发表日期：2024
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S-MGBs bearing amidine tail groups are potent, selective antiplasmodial agents.

带有脒基尾部的 S-MGB 是强效、选择性的抗疟原虫药物

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d4md00619d
Perieteanu Marina, Garzon Tayner Rodriguez, McGee Leah M C, Khalaf Abedawn I, Suckling Colin J, Beveridge Rebecca, Avery Vicky M, Scott Fraser J
发表日期：2024
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Protection against lung pathology during obesity-accelerated ageing in mice by the parasitic worm product ES-62

寄生虫产物ES-62对肥胖加速衰老小鼠肺部病变的保护作用

期刊:Frontiers in Immunology
影响因子:
doi:10.3389/fimmu.2023.1285069
Harnett, Margaret M; Lumb, Felicity E; Crowe, Jenny; Doonan, James; Buitrago, Geraldine; Brown, Stephanie; Thom, Gillian; MacDonald, Amy; Suckling, Colin J; Selman, Colin; Harnett, William
微生物学
肥胖
衰老
代谢
发表日期：2023
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Multitargeted anti-infective drugs: resilience to resistance in the antimicrobial resistance era

多靶点抗感染药物：在抗菌素耐药时代抵御耐药性的挑战

期刊:
影响因子:
doi:10.4155/fdd-2022-0001
Suckling, Colin J; Hunter, Iain S; Scott, Fraser J
炎症/感染
发表日期：2022
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Correction: Truncated S-MGBs: towards a parasite-specific and low aggregation chemotype

更正：截短的S-MGBs：朝着寄生虫特异性和低聚集化学型发展

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d1md90044g
Brooke, Daniel P; McGee, Leah M C; Giordani, Federica; Cross, Jasmine M; Khalaf, Abedawn I; Irving, Craig; Gillingwater, Kirsten; Shaw, Craig D; Carter, Katharine C; Barrett, Michael P; Suckling, Colin J; Scott, Fraser J
微生物学
发表日期：2021
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Selective in vitro anti-cancer activity of non-alkylating minor groove binders

非烷基化小沟结合剂的选择性体外抗癌活性

期刊:Medchemcomm
影响因子:
doi:10.1039/c9md00268e
Nichol, Ryan J O; Khalaf, Abedawn I; Sooda, Kartheek; Hussain, Omar; Griffiths, Hollie B S; Phillips, Roger; Javid, Farideh A; Suckling, Colin J; Allison, Simon J; Scott, Fraser J
肿瘤
肿瘤免疫
发表日期：2019
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Protection Against Arthritis by the Parasitic Worm Product ES-62, and Its Drug-Like Small Molecule Analogues, Is Associated With Inhibition of Osteoclastogenesis

寄生虫产物ES-62及其类药小分子类似物对关节炎的保护作用与抑制破骨细胞生成有关。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2018.01016
Doonan, James; Lumb, Felicity E; Pineda, Miguel A; Tarafdar, Anuradha; Crowe, Jenny; Khan, Aneesah M; Suckling, Colin J; Harnett, Margaret M; Harnett, William
细胞生物学
微生物学
关节炎
发表日期：2018
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Small Molecule Analogues of the parasitic worm product ES-62 interact with the TIR domain of MyD88 to inhibit pro-inflammatory signalling

寄生虫产物ES-62的小分子类似物与MyD88的TIR结构域相互作用，从而抑制促炎信号传导。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-018-20388-z
Suckling, Colin J; Alam, Shahabuddin; Olson, Mark A; Saikh, Kamal U; Harnett, Margaret M; Harnett, William
微生物学
信号转导
发表日期：2018
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Dendritic cells provide a therapeutic target for synthetic small molecule analogues of the parasitic worm product, ES-62

树突状细胞为寄生虫产物 ES-62 的合成小分子类似物提供了一个治疗靶点。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-017-01651-1
Lumb, Felicity E; Doonan, James; Bell, Kara S; Pineda, Miguel A; Corbet, Marlene; Suckling, Colin J; Harnett, Margaret M; Harnett, William
树突状细胞
微生物学
细胞生物学
树突状细胞
免疫/内分泌
发表日期：2017
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Structure-based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1

基于结构的抗寄生虫吡咯并嘧啶类药物的设计与合成，靶向蝶啶还原酶1

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm500483b
Khalaf, Abedawn I; Huggan, Judith K; Suckling, Colin J; Gibson, Colin L; Stewart, Kirsten; Giordani, Federica; Barrett, Michael P; Wong, Pui Ee; Barrack, Keri L; Hunter, William N
微生物学
发表日期：2014
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