日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation

亲和力和协同作用调节三元复合物的形成以驱动目标蛋白质降解

Ryan P Wurz, Huan Rui, Ken Dellamaggiore, Sudipa Ghimire-Rijal, Kaylee Choi, Kate Smither, Albert Amegadzie, Ning Chen, Xiaofen Li, Abhisek Banerjee, Qing Chen, Dane Mohl, Amit Vaish

Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies

使用收集的 83 种支架一致的单克隆抗体的综合分析数据集开发计算机模型来预测粘度和小鼠清除率

Marissa Mock, Alex W Jacobitz, Christopher James Langmead, Athena Sudom, Daniel Yoo, Sara C Humphreys, Mai Alday, Larysa Alekseychyk, Nicolas Angell, Vivian Bi, Hannah Catterall, Chen-Chun Chen, Hui-Ting Chou, Kip P Conner, Kevin D Cook, Ana R Correia, Andrew Dykstra, Sudipa Ghimire-Rijal, Kevin Gra

Structural basis for pharmacological modulation of the TRPC6 channel

TRPC6 通道药理调节的结构基础

Yonghong Bai #, Xinchao Yu #, Hao Chen, Daniel Horne, Ryan White, Xiaosu Wu, Paul Lee, Yan Gu, Sudipa Ghimire-Rijal, Daniel C-H Lin, Xin Huang

Activation of the HIF prolyl hydroxylase by the iron chaperones PCBP1 and PCBP2

铁伴侣分子 PCBP1 和 PCBP2 激活 HIF 脯氨酰羟化酶

Anjali Nandal, Julio C Ruiz, Poorna Subramanian, Sudipa Ghimire-Rijal, Ruth Ann Sinnamon, Timothy L Stemmler, Richard K Bruick, Caroline C Philpott