文献库，生知库 | 链接生命科学的每一步

日期影响因子

Rapid Drug Sensitivity Profiling via a Novel High-Success-Rate Culture Method for Patient-Derived Pancreatic Cancer: An Exploratory Preclinical Platform for Advancing Clinical Applications and Drug Development

利用新型高成功率培养方法对患者来源的胰腺癌细胞进行快速药物敏感性分析：一个用于推进临床应用和药物开发的探索性临床前平台

影响因子:5.2

doi:10.3390/cells15040313

Kato, Yu; Yamamoto, Naoki; Uchida, Yuichiro; Hiramatsu, Noriko; Ozeki, Takato; Minobe, Yukari; Hasegawa, Yukika; Kawabe, Sho; Yabuuchi, Hikaru; Yamada, Seiji; Hata, Yuko; Sugihara, Eiji; Takimoto, Tetsuya; Saito, Kuniaki; Takahara, Takeshi; Suda, Koichi; Nagano, Osamu; Saya, Hideyuki

细胞生物学

发表日期：2026

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Genomic Profiling in Localized Prostate Cancer: Associations With Biochemical Recurrence and Response to Salvage Radiotherapy

局限性前列腺癌的基因组分析：与生化复发和挽救性放疗反应的关联

期刊:Cancer Science

影响因子:4.3

doi:10.1111/cas.70367

Zennami, Kenji; Takimoto, Tetsuya; Nukaya, Takuhisa; Sumitomo, Makoto; Takeda, Mayu; Sugihara, Eiji; Saya, Hideyuki; Shiroki, Ryoichi

发表日期：2026

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Intrachromosomal insertion as a diagnostic challenge: a hidden structural rearrangement causing recurrent duplication and deletion

染色体内插入作为诊断难题：一种隐匿的结构重排导致反复的重复和缺失

期刊:Molecular Cytogenetics

影响因子:1.4

doi:10.1186/s13039-026-00748-5

Kawamura, Rie; Shichiri, Yui; Suzuki, Hideki; Murase, Yuri; Naru, Yuki; Hara, Tetsuaki; Tsuboi, Ayana; Satano, Hanae; Sugihara, Eiji; Kurahashi, Hiroki

发表日期：2026

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Benzaldehyde suppresses epithelial-mesenchymal plasticity and overcomes treatment resistance in cancer by targeting the interaction of 14-3-3ζ with H3S28ph

苯甲醛通过靶向14-3-3ζ与H3S28ph的相互作用，抑制上皮-间质可塑性并克服癌症治疗耐药性。

期刊:British Journal of Cancer

影响因子:6.8

doi:10.1038/s41416-025-03006-4

Saito, Jun; Onishi, Nobuyuki; Yamasaki, Juntaro; Koike, Naoyoshi; Hata, Yukie; Kimura, Kiyomi; Otsuki, Yuji; Nobusue, Hiroyuki; Sampetrean, Oltea; Shimizu, Takatsune; Okazaki, Shogo; Sugihara, Eiji; Saya, Hideyuki

发表日期：2025

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Significance of homologous recombinant deficiency as a biomarker for drug sensitivity in colorectal cancer.

同源重组缺陷作为结直肠癌药物敏感性生物标志物的意义

期刊:British Journal of Cancer

影响因子:6.8

doi:10.1038/s41416-025-02950-5

Kato Yujin, Seishima Ryo, Hattori Kaoru, Kato Hirochika, Ishida Hiroki, Shigeta Kohei, Okabayashi Koji, Sugihara Eiji, Takimoto Tetsuya, Nakamura Kohei, Nishihara Hiroshi, Saya Hideyuki, Kitagawa Yuko

发表日期：2025

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Mutation Analysis of TMB-High Colorectal Cancer: Insights Into Molecular Pathways and Clinical Implications

TMB高表达型结直肠癌的突变分析：分子通路和临床意义的深入探讨

期刊:Cancer Science

影响因子:4.3

doi:10.1111/cas.16455

Chikaishi, Yuko; Matsuoka, Hiroshi; Sugihara, Eiji; Takeda, Mayu; Sumitomo, Makoto; Yamada, Seiji; Inaguma, Gaku; Omura, Yusuke; Cheong, Yeongcheol; Kobayashi, Yosuke; Nakauchi, Masaya; Hiro, Junichiro; Masumori, Koji; Otsuka, Koki; Nishihara, Hiroshi; Suda, Koichi; Saya, Hideyuki; Takimoto, Tetsuya

发表日期：2025

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LCN2-mediated ferroptosis resistance in tissue homeostasis and early-stage tumorigenesis of the fallopian tube epithelium.

LCN2介导的铁死亡抵抗在输卵管上皮组织稳态和早期肿瘤发生中的作用

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2025.112654

Imaeda Keiyo, Tamura Tomohiro, Nagai Shimpei, Sugihara Eiji, Yamasaki Juntaro, Otsuki Yuji, Nakamura Kohei, Takeda Takashi, Nakamura Kanako, Nogami Yuya, Tsuji Kosuke, Chiyoda Tatsuyuki, Kisu Iori, Kobayashi Yusuke, Banno Kouji, Yamaguchi Rui, Sakurada Kazuhiro, Saya Hideyuki, Aoki Daisuke, Ahmed Ahmed Ashour, Nagano Osamu, Masuda Kenta, Yamagami Wataru

发表日期：2025

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Impact of TSC2 loss on progression-free survival in uterine carcinosarcoma: A retrospective analysis

TSC2缺失对子宫癌肉瘤无进展生存期的影响：一项回顾性分析

期刊:Fujita Medical Journal

doi:10.20407/fmj.2025-001

Ichikawa, Ryoko; Sudo, Tamotsu; Takada, Kyohei; Ohwaki, Akiko; Ito, Mayuko; Shimizu, Yusuke; Takeda, Mayu; Sugihara, Eiji; Takimoto, Tetsuya; Nishizawa, Haruki

发表日期：2025

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Comprehensive Search for Genes Involved in Thalidomide Teratogenicity Using Early Differentiation Models of Human Induced Pluripotent Stem Cells: Potential Applications in Reproductive and Developmental Toxicity Testing

利用人诱导多能干细胞早期分化模型全面筛选与沙利度胺致畸性相关的基因：在生殖和发育毒性测试中的潜在应用

doi:10.3390/cells14030215

Kato, Yu; Inaba, Takeshi; Shinke, Koudai; Hiramatsu, Noriko; Horie, Tetsuhiro; Sakamoto, Takuya; Hata, Yuko; Sugihara, Eiji; Takimoto, Tetsuya; Nagai, Noriaki; Ishigaki, Yasuhito; Kojima, Hajime; Nagano, Osamu; Yamamoto, Naoki; Saya, Hideyuki

发育与干细胞

细胞生物学

发表日期：2025

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Comparative Analysis of Two NGS-Based Platforms for Product-of-Conception Karyotyping

两种基于NGS技术的胚胎核型分析平台比较分析

影响因子:2.8

doi:10.3390/genes15081100

Murase, Yuri; Shichiri, Yui; Inagaki, Hidehito; Nakano, Tatsuya; Nakaoka, Yoshiharu; Morimoto, Yoshiharu; Ichikawa, Tomoko; Nishizawa, Haruki; Sugihara, Eiji; Kurahashi, Hiroki

发表日期：2024

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