日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

High-throughput screening identifies a trafficking corrector for long QT syndrome-associated KCNQ1 variants

高通量筛选鉴定出一种与长QT综合征相关的KCNQ1变异体的转运校正因子

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.201297
Moster, Katherine R Clowes; Vanoye, Carlos G; Chang-Gonzalez, Ana C; Romaine, Ian M; Stefanski, Katherine M; Wilkinson, Mason C; Bauer, Joshua A; Hasaka, Thomas P; Days, Emily L; Desai, Reshma R; Butcher, Kathryn R; Sulikowski, Gary A; Waterson, Alex G; Meiler, Jens; Ledwitch, Kaitlyn V; George, Alfred L Jr; Sanders, Charles R
发表日期：2026
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Time-Resolved Analysis of Protein-Protein Ensembles Using a Destabilizing Domain to Map Dynamic Interactions of SARS-CoV-2 nsp15

利用去稳定结构域对蛋白质-蛋白质复合物进行时间分辨分析，以绘制SARS-CoV-2 nsp15的动态相互作用图谱

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.5c00377
Cameron, Crissey; Clark, R Mason; Metts, Adam M; Jiang, Runze M; Scaggs, Toya D; Kim, Kwangho; Sulikowski, Gary A; Plate, Lars
SARS-CoV-2
发表日期：2025
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Photoaffinity Ligand of Cystic Fibrosis Corrector VX-445 Identifies SCCPDH as an Off-Target.

囊性纤维化矫正剂 VX-445 的光亲和配体鉴定出 SCCPDH 为脱靶靶点

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.5c00157
Kim Minsoo, Kim Kwangho, Lee Jesun, Barny Lea A, Scaggs Toya D, Romaine Ian M, Jeon KyuOk, Codreanu Simona G, Sherrod Stacy D, McLean John A, Naren Anjaparavanda P, Sulikowski Gary A, Plate Lars
发表日期：2025
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High Throughput Screening Identifies a Small Molecule Trafficking Corrector for Long-QT Syndrome Associated KCNQ1 Variants

高通量筛选鉴定出一种针对长QT综合征相关KCNQ1变异的小分子转运校正剂

期刊:
影响因子:
doi:10.1101/2025.10.13.682066
Moster, Katherine R Clowes; Vanoye, Carlos G; Chang-Gonzalez, Ana C; Romaine, Ian M; Stefanski, Katherine M; Wilkinson, Mason C; Bauer, Joshua A; Hasaka, Thomas P; Days, Emily L; Desai, Reshma R; Butcher, Kathryn R; Sulikowski, Gary A; Waterson, Alex G; Meiler, Jens; Ledwitch, Kaitlyn V; George, Alfred L Jr; Sanders, Charles R
发表日期：2025
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Properties of Configurationally Stable Atropoenantiomers in Macrocyclic Natural Products and the Chrysophaentin Family

大环天然产物和金丝桃素家族中构型稳定的阻转对映异构体的性质

期刊:Accounts of Chemical Research
影响因子:17.7
doi:10.1021/acs.accounts.2c00648
Bewley, Carole A; Sulikowski, Gary A; Yang, Zhongyue J; Bifulco, Giuseppe; Cho, Hyo-Moon; Fullenkamp, Christopher R
发表日期：2023
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Screen for Small-Molecule Modulators of Circadian Rhythms Reveals Phenazine as a Redox-State Modifying Clockwork Tuner

筛选昼夜节律小分子调节剂发现吩嗪是一种氧化还原状态调节剂，可调控生物钟。

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.2c00240
Kelly, Kevin P; Borsetti, Hugo; Wenzler, Marta E; Ustione, Alessandro; Kim, Kwangho; Christov, Plamen P; Ramirez, Bianca; Bauer, Joshua A; Piston, David W; Johnson, Carl Hirschie; Sulikowski, Gary A
信号转导
发表日期：2022
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VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels

VU6036720：首个高效选择性异源Kir4.1/5.1内向整流钾通道体外抑制剂

期刊:Molecular Pharmacology
影响因子:3
doi:10.1124/molpharm.121.000464
McClenahan, Samantha J; Kent, Caitlin N; Kharade, Sujay V; Isaeva, Elena; Williams, Jade C; Han, Changho; Terker, Andrew; Gresham, Robert 3rd; Lazarenko, Roman M; Days, Emily L; Romaine, Ian M; Bauer, Joshua A; Boutaud, Olivier; Sulikowski, Gary A; Harris, Raymond; Weaver, C David; Staruschenko, Alexander; Lindsley, Craig W; Denton, Jerod S
发表日期：2022
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Simultaneous Exposure to Intracellular and Extracellular Photosensitizers for the Treatment of Staphylococcus aureus Infections

同时使用细胞内和细胞外光敏剂治疗金黄色葡萄球菌感染

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00919-21
Drury, Sydney L; Miller, Anderson R; Laut, Clare L; Walter, Alec B; Bennett, Monique R; Su, Meng; Bai, Mingfeng; Jing, Bingwen; Joseph, Scott B; Metzger, Edward J; Bane, Charles E; Black, Chad C; Macdonald, Mary T; Dutter, Brendan F; Romaine, Ian M; Waterson, Alex G; Sulikowski, Gary A; Jansen, E Duco; Crowe, James E Jr; Sciotti, Richard J; Skaar, Eric P
炎症/感染
细胞生物学
发表日期：2021
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Optimization of ether and aniline based inhibitors of lactate dehydrogenase

乳酸脱氢酶醚类和苯胺类抑制剂的优化

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2021.127974
Christov, Plamen P; Kim, Kwangho; Jana, Somnath; Romaine, Ian M; Rai, Ganesha; Mott, Bryan T; Allweil, Alexander A; Lamers, Alexander; Brimacombe, Kyle R; Urban, Daniel J; Lee, Tobie D; Hu, Xin; Lukacs, Christine M; Davies, Douglas R; Jadhav, Ajit; Hall, Matthew D; Green, Neal; Moore, William J; Stott, Gordon M; Flint, Andrew J; Maloney, David J; Sulikowski, Gary A; Waterson, Alex G
发表日期：2021
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Synthesis of 9-Dechlorochrysophaentin A Enables Studies Revealing Bacterial Cell Wall Biosynthesis Inhibition Phenotype in B. subtilis

9-脱氯金霉素A的合成使得研究能够揭示枯草芽孢杆菌中细菌细胞壁生物合成抑制表型。

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.0c04917
Fullenkamp, Christopher R; Hsu, Yen-Pang; Quardokus, Ellen M; Zhao, Gengxiang; Bewley, Carole A; VanNieuwenhze, Michael; Sulikowski, Gary A
微生物学
细胞生物学
发表日期：2020
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