日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Excess cysteine drives conjugate formation and impairs proliferation of NRF2-activated cancer cells

过量的半胱氨酸会促进结合物的形成,并抑制NRF2激活的癌细胞增殖。

Brain, Jennifer A; Vigil, Anna-Lena B G; Davidsen, Kristian; Itokawa, Ayaha; Jurasin, Abby C; Kerbyson, Hannah J; Kobiesa, Maximilian; Hart, Madeleine L; Yoon, Sang Jun; Bellotti, Peter; Maianti, Juan Pablo; DeNicola, Gina M; Sullivan, Lucas B

Damage-induced pyroptosis drives endogenous thymic regeneration by activating the purinergic receptor P2Y2.

损伤诱导的细胞焦亡通过激活嘌呤能受体 P2Y2 来驱动内源性胸腺再生。

Kinsella Sinéad, Evandy Cindy A, Cooper Kirsten, Kirsche Erin, Warren Makya, deRoos Paul, Cardinale Antonella, Iovino Lorenzo, Granadier David, Smith Colton W, Hopwo Kayla, Sullivan Lucas B, Velardi Enrico, Dudakov Jarrod A

Ribosome-associated quality control of aberrant protein production during amino acid limitation

氨基酸限制期间核糖体相关的异常蛋白质合成质量控制

Darnell, Alicia M; Chidley, Christopher; Paradise, Victoria; Cui, Danica S; Davidsen, Kristian; Lincoln, Sarah C; Abbott, Keene L; Elbashir, Ryan; Vander Heiden, Campbell P; Sorger, Peter K; Sullivan, Lucas B; Davis, Joseph H; Vander Heiden, Matthew G

In vivo functional screens reveal KEAP1 loss as a driver of chemoresistance in small cell lung cancer.

体内功能筛选揭示 KEAP1 缺失是小细胞肺癌化疗耐药性的驱动因素

Brumage Lauren, Best Scott, Hippe Daniel S, Grunblatt Eli, Chanana Pritha, Wu Feinan, Lee Myung Chang, Ying Zhe, Ibrahim Ali, Chung Jae Heun, Vigil Anna, Fatherree Jackson, Beronja Slobodan, Paddison Patrick, Sullivan Lucas, Nabet Barzin, MacPherson David

Defined media reveal the essential role of lipid scavenging in supporting cancer cell proliferation

明确的培养基揭示了脂质清除在支持癌细胞增殖中的关键作用。

Newsom, Oliver J; Zheng, Eric; Sullivan, Lucas B

Cytokine and metabolite networks shape T cell residency and functionality at the term human maternal-fetal interface

细胞因子和代谢物网络塑造了足月人类母胎界面处T细胞的驻留和功能。

Maurice, Nicholas J; Erickson, Jami R; DeJong, Caitlin S; Mair, Florian; Taber, Alexis K; Frutoso, Marie; Islas, Laura V; Vigil, Anna Lena B G; Lawler, Richard L; McElrath, Juliana; Newell, Evan; Sullivan, Lucas B; Shree, Raj; McCartney, Stephen A

Recurrent Breast Cancer Cells Depend on De novo Pyrimidine Biosynthesis to Suppress Ferroptosis

复发性乳腺癌细胞依赖于从头合成嘧啶来抑制铁死亡

McCutcheon, Kelley R; Wu, Josh; Ozdemir, Yasemin Ceyhan; McKinney, Brock J; Srinivasan, Sharan; Itokawa, Ayaha; Newsom, Oliver J; Vigil, Anna; Fox, Douglas B; Sullivan, Lucas B; Alvarez, James V

Defined media reveals the essential role of lipid scavenging to support cancer cell proliferation.

明确的培养基揭示了脂质清除在支持癌细胞增殖中的重要作用

Newsom Oliver J, Sullivan Lucas B

A robust method for measuring aminoacylation through tRNA-Seq

一种通过tRNA-Seq测量氨酰化的可靠方法

Davidsen, Kristian; Sullivan, Lucas B

Combined Germline and Mosaic SDHA Mutation Is Associated With a Multicancer Syndrome Including Neuroblastoma, Renal Cancer, and Multifocal GI Tumor

生殖系和嵌合型SDHA突变相结合与多种癌症综合征相关,包括神经母细胞瘤、肾癌和多灶性胃肠道肿瘤。

Cranmer, Lee D; Konnick, Eric Q; Yoshida, Jennifer R; Jacobson, Angela L; Malik, Bilal A; Mogal, Harveshp; Sullivan, Lucas B; Handfrod, Cynthia L; Pritchard, Colin C; Dubard-Gault, Marianne E