日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Gene Editing in Dimorphic Fungi Using CRISPR/Cas9.

利用 CRISPR/Cas9 对二型真菌进行基因编辑

Kujoth Gregory C, Sullivan Thomas D, Klein Bruce S

CRISPR/Cas9-Mediated Gene Disruption Reveals the Importance of Zinc Metabolism for Fitness of the Dimorphic Fungal Pathogen Blastomyces dermatitidis

CRISPR/Cas9介导的基因敲除揭示了锌代谢对双相型真菌病原体皮炎芽生菌适应性的重要性

Kujoth, Gregory C; Sullivan, Thomas D; Merkhofer, Richard; Lee, Taek-Jin; Wang, Huafeng; Brandhorst, Tristan; Wüthrich, Marcel; Klein, Bruce S

Fungal Mimicry of a Mammalian Aminopeptidase Disables Innate Immunity and Promotes Pathogenicity

真菌对哺乳动物氨肽酶的模拟会削弱先天免疫力并促进致病性

Sterkel, Alana K; Lorenzini, Jenna L; Fites, J Scott; Subramanian Vignesh, Kavitha; Sullivan, Thomas D; Wuthrich, Marcel; Brandhorst, Tristan; Hernandez-Santos, Nydiaris; Deepe, George S Jr; Klein, Bruce S

The Dynamic Genome and Transcriptome of the Human Fungal Pathogen Blastomyces and Close Relative Emmonsia

人类真菌病原体芽生菌及其近缘种埃蒙氏菌的动态基因组和转录组

Muñoz, José F; Gauthier, Gregory M; Desjardins, Christopher A; Gallo, Juan E; Holder, Jason; Sullivan, Thomas D; Marty, Amber J; Carmen, John C; Chen, Zehua; Ding, Li; Gujja, Sharvari; Magrini, Vincent; Misas, Elizabeth; Mitreva, Makedonka; Priest, Margaret; Saif, Sakina; Whiston, Emily A; Young, Sarah; Zeng, Qiandong; Goldman, William E; Mardis, Elaine R; Taylor, John W; McEwen, Juan G; Clay, Oliver K; Klein, Bruce S; Cuomo, Christina A

Identification of the mating-type (MAT) locus that controls sexual reproduction of Blastomyces dermatitidis

鉴定控制皮炎芽生菌有性生殖的交配型(MAT)基因座

Li, Wenjun; Sullivan, Thomas D; Walton, Eric; Averette, Anna Floyd; Sakthikumar, Sharadha; Cuomo, Christina A; Klein, Bruce S; Heitman, Joseph

SREB, a GATA transcription factor that directs disparate fates in Blastomyces dermatitidis including morphogenesis and siderophore biosynthesis

SREB是一种GATA转录因子,它指导皮炎芽生菌中多种不同的命运,包括形态发生和铁载体生物合成。

Gauthier, Gregory M; Sullivan, Thomas D; Gallardo, Sergio S; Brandhorst, T Tristan; Vanden Wymelenberg, Amber J; Cuomo, Christina A; Suen, Garret; Currie, Cameron R; Klein, Bruce S

Discordant influence of Blastomyces dermatitidis yeast-phase-specific gene BYS1 on morphogenesis and virulence

皮炎芽生菌酵母相特异性基因 BYS1 对形态发生和毒力的不一致影响

Krajaejun, Theerapong; Wüthrich, Marcel; Gauthier, Gregory M; Warner, Thomas F; Sullivan, Thomas D; Klein, Bruce S

Genetic diversity in Blastomyces dermatitidis: implications for PCR detection in clinical and environmental samples

皮炎芽生菌的遗传多样性:对临床和环境样本中PCR检测的意义

Meece, Jennifer K; Anderson, Jennifer L; Klein, Bruce S; Sullivan, Thomas D; Foley, Steven L; Baumgardner, Dennis J; Brummitt, Charles F; Reed, Kurt D

The 74-kilodalton immunodominant antigen of the pathogenic oomycete Pythium insidiosum is a putative exo-1,3-beta-glucanase

致病性卵菌腐霉菌(Pythium insidiosum)的74千道尔顿免疫优势抗原是一种推定的外切-1,3-β-葡聚糖酶。

Krajaejun, Theerapong; Keeratijarut, Angsana; Sriwanichrak, Kanchana; Lowhnoo, Tassanee; Rujirawat, Thidarat; Petchthong, Thanom; Yingyong, Wanta; Kalambaheti, Thareerat; Smittipat, Nat; Juthayothin, Tada; Sullivan, Thomas D

Agrobacterium tumefaciens integrates transfer DNA into single chromosomal sites of dimorphic fungi and yields homokaryotic progeny from multinucleate yeast

根癌农杆菌将转移DNA整合到二态真菌的单个染色体位点,并从多核酵母中产生同核子代。

Sullivan, Thomas D; Rooney, Peggy J; Klein, Bruce S