文献库，生知库 | 链接生命科学的每一步

日期影响因子

Molecular characterisation of Toxoplasma gondii Mre11 reveals unique structural features and potential as a therapeutic target

弓形虫Mre11的分子特征分析揭示了其独特的结构特征及其作为治疗靶点的潜力

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-27759-3

Ruiz, Diego M; Turowski, Valeria R; Sullivan, William J Jr; Angel, Sergio O

发表日期：2025

文献求助收藏

GCN5a is a telomeric lysine acetyltransferase whose loss primes Toxoplasma gondii for latency

GCN5a是一种端粒赖氨酸乙酰转移酶，其缺失会使弓形虫进入潜伏期。

影响因子:3.1

doi:10.1128/msphere.00026-25

Dey, Vishakha; Holmes, Michael J; Srivastava, Sandeep; Wilson, Emma H; Sullivan, William J Jr

发表日期：2025

文献求助收藏

Toxoplasma gondii RAD51 recombinase is required to overcome DNA replication stress and its inactivation leads to bradyzoite differentiation.

弓形虫 RAD51 重组酶是克服 DNA 复制压力所必需的，其失活会导致缓殖子分化。

doi:10.1101/2025.04.08.647840

Cartagena Ana M Saldarriaga, Arias AyelÃ©n Aparicio, Cristaldi Constanza, Ganuza Agustina, Gonzalez M Micaela, Corvi MarÃa M, Sullivan William J Jr, Vanagas Laura, Angel Sergio O

发表日期：2025

文献求助收藏

321 Application of the Fick Principle for the study of visceral nutrient absorption and metabolism

321 菲克原理在内脏营养吸收和代谢研究中的应用

doi:10.1128/EC.05117-11

Konrad, Christian; Wek, Ronald C; Sullivan, William J Jr; Harmon, David L; Huntington, Gerald B

发表日期：2024

文献求助收藏

Toxoplasma gondii AP2XII-2 Contributes to Transcriptional Repression for Sexual Commitment.

弓形虫 AP2XII-2 参与性承诺的转录抑制

影响因子:3.1

doi:10.1128/msphere.00606-22

Srivastava Sandeep, Holmes Michael J, White Michael W, Sullivan William J Jr

发表日期：2023

文献求助收藏

Eukaryotic Initiation Factor 2α Kinases Regulate Virulence Functions, Stage Conversion, and the Stress Response in Entamoeba invadens

真核起始因子2α激酶调控侵袭性内阿米巴的毒力功能、阶段转换和应激反应

影响因子:3.1

doi:10.1128/msphere.00131-22

Walters, Heather A; Welter, Brenda H; Moss, Harrison C; Villano, Martha A; Orobio-Hurtado, Ronny; Sullivan, William J Jr; Temesvari, Lesly A

发表日期：2022

文献求助收藏

TgIF2K-B Is an eIF2α Kinase in Toxoplasma gondii That Responds to Oxidative Stress and Optimizes Pathogenicity

TgIF2K-B是弓形虫中的一种eIF2α激酶，它响应氧化应激并优化致病性。

影响因子:4.7

doi:10.1128/mBio.03160-20

Augusto, Leonardo; Martynowicz, Jennifer; Amin, Parth H; Carlson, Kenneth R; Wek, Ronald C; Sullivan, William J Jr

发表日期：2021

文献求助收藏

Host sensing and signal transduction during Toxoplasma stage conversion

弓形虫阶段转换过程中的宿主感知和信号转导

期刊:Molecular Microbiology

影响因子:2.6

doi:10.1111/mmi.14634

Augusto, Leonardo; Wek, Ronald C; Sullivan, William J Jr

发表日期：2021

文献求助收藏

Emerging Therapeutic Targets Against Toxoplasma gondii: Update on DNA Repair Response Inhibitors and Genotoxic Drugs

弓形虫病的新兴治疗靶点：DNA修复反应抑制剂和基因毒性药物的最新进展

期刊:Frontiers in Cellular and Infection Microbiology

影响因子:4.8

doi:10.3389/fcimb.2020.00289

Angel, Sergio O; Vanagas, Laura; Ruiz, Diego M; Cristaldi, Constanza; Saldarriaga Cartagena, Ana M; Sullivan, William J Jr

发表日期：2020

文献求助收藏

Efficacy of Guanabenz Combination Therapy against Chronic Toxoplasmosis across Multiple Mouse Strains

胍那苄联合疗法对多种小鼠慢性弓形虫病的疗效

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/AAC.00539-20

Martynowicz, Jennifer; Doggett, J Stone; Sullivan, William J Jr

发表日期：2020

文献求助收藏