Sumit J相关文献与解析，生知库 | 链接生命科学的每一步

The far extracellular CUB domain of the adhesion GPCR ADGRG6/GPR126 is a key regulator of receptor signaling

粘附型GPCR ADGRG6/GPR126的远端胞外CUB结构域是受体信号传导的关键调节因子。

期刊:Proceedings of the National Academy of Sciences of the United States of America

Bandekar, Sumit J; Dintzner, Ethan E; Leon, Katherine; Kordon, Szymon P; Slezak, Tomasz; Cechova, Kristina; Vafabakhsh, Reza; Araç, Demet

Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function

细胞外和跨膜结构域之间的构象耦合调节全粘附 GPCR 功能

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-54836-4

Szymon P Kordon #, Kristina Cechova #, Sumit J Bandekar, Katherine Leon, Przemysław Dutka, Gracie Siffer, Anthony A Kossiakoff, Reza Vafabakhsh, Demet Araç1

Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder

合成粘合剂对粘附 GPCR ADGRL3/Latrophilin3 的异构体和配体特异性调节

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-023-36312-7

Szymon P Kordon, Przemysław Dutka, Justyna M Adamska, Sumit J Bandekar, Katherine Leon, Satchal K Erramilli, Brock Adams, Jingxian Li, Anthony A Kossiakoff, Demet Araç

The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms

黏附性G蛋白偶联受体CELSR1-3和LPHN3通过不同的激活机制与G蛋白结合。

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2023.112552

Duy Lan Huong Bui,Andrew Roach,Jingxian Li,Sumit J Bandekar,Elizabeth Orput,Ritika Raghavan,Demet Araç,Richard C Sando

The structure of fly Teneurin-m reveals an asymmetric self-assembly that allows expansion into zippers

蝇类Teneurin-m的结构揭示了一种不对称的自组装，可以扩展成拉链

期刊:EMBO Reports

影响因子:6.5

doi:10.15252/embr.202256728

Jingxian Li #, Sumit J Bandekar #, Demet Araç

信号转导

发表日期：2023

文献求助收藏

Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1

Trio的结构/功能研究揭示了其构型，并表明保守的连接元件增强了其对Rac1的活性。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2022.102209

Bandekar, Sumit J; Chen, Chun-Liang; Ravala, Sandeep K; Cash, Jennifer N; Avramova, Larisa V; Zhalnina, Mariya V; Gutkind, J Silvio; Li, Sheng; Tesmer, John J G

发表日期：2022

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Interim Analysis of STREAMLINE(®) Surgical System Clinical Outcomes in Eyes with Glaucoma

STREAMLINE®手术系统治疗青光眼患者的临床结果中期分析

期刊:

影响因子:

doi:10.2147/OPTH.S358871

Lazcano-Gomez, Gabriel; Garg, Sumit J; Yeu, Elizabeth; Kahook, Malik Y

Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential

Trio 的 C 端鸟嘌呤核苷酸交换因子模块在自抑制构象中的结构揭示了其致癌潜力

期刊:Science Signaling

影响因子:

doi:10.1126/scisignal.aav2449

Sumit J Bandekar, Nadia Arang, Ena S Tully, Brittany A Tang, Brenna L Barton, Sheng Li, J Silvio Gutkind, John J G Tesmer

肿瘤

发表日期：2019

文献求助收藏

11-Oxoeicosatetraenoic acid is a cyclooxygenase-2/15-hydroxyprostaglandin dehydrogenase-derived antiproliferative eicosanoid

11-氧代二十碳四烯酸是一种环氧合酶-2/15-羟基前列腺素脱氢酶衍生的抗增殖类二十烷酸

期刊:Chemical Research in Toxicology

影响因子:3.7

doi:10.1021/tx200336f

Xiaojing Liu, Suhong Zhang, Jasbir S Arora, Nathaniel W Snyder, Sumit J Shah, Ian A Blair

发表日期：2011

文献求助收藏

Structural basis for regulation of CELSR1 by a compact module in its extracellular region.

CELSR1 胞外区紧凑模块调控的结构基础

The far extracellular CUB domain of the adhesion GPCR ADGRG6/GPR126 is a key regulator of receptor signaling

粘附型GPCR ADGRG6/GPR126的远端胞外CUB结构域是受体信号传导的关键调节因子。

Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function

细胞外和跨膜结构域之间的构象耦合调节全粘附 GPCR 功能

Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder

合成粘合剂对粘附 GPCR ADGRL3/Latrophilin3 的异构体和配体特异性调节

The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms

黏附性G蛋白偶联受体CELSR1-3和LPHN3通过不同的激活机制与G蛋白结合。

The structure of fly Teneurin-m reveals an asymmetric self-assembly that allows expansion into zippers

蝇类Teneurin-m的结构揭示了一种不对称的自组装，可以扩展成拉链

Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1

Trio的结构/功能研究揭示了其构型，并表明保守的连接元件增强了其对Rac1的活性。

Interim Analysis of STREAMLINE(®) Surgical System Clinical Outcomes in Eyes with Glaucoma

STREAMLINE®手术系统治疗青光眼患者的临床结果中期分析

Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential

Trio 的 C 端鸟嘌呤核苷酸交换因子模块在自抑制构象中的结构揭示了其致癌潜力

11-Oxoeicosatetraenoic acid is a cyclooxygenase-2/15-hydroxyprostaglandin dehydrogenase-derived antiproliferative eicosanoid

11-氧代二十碳四烯酸是一种环氧合酶-2/15-羟基前列腺素脱氢酶衍生的抗增殖类二十烷酸