Matrix-directed therapy losartan to identify the effect on the bone resorption marker carboxy-terminal crosslink of type I collagen telopeptide (CTX) in older adolescents and adults with osteogenesis imperfecta recruited from secondary care sites: the 'MOI-A' study; a randomised, phase 2/pilot, dose-escalating trial
基质导向疗法氯沙坦对骨吸收标志物I型胶原蛋白端肽羧基末端交联(CTX)的影响:一项随机、II期/试点、剂量递增试验,研究对象为来自二级医疗机构的成骨不全青少年和成人患者:MOI-A研究;
期刊:BMJ Open
影响因子:2.3
doi:10.1136/bmjopen-2025-107243
Haji Sadeghi, Mahboobeh; Cohen, Judith; Williams, Bronwen; Wilkinson, Amy; Sumpter, Sarah; Simms, Laura; Huang, Chao; Pugh, Keith; Heath, Charlotte; Sangiorgi, Luca; Gurioli, Francesca; Gnoli, Maria; Moroni, Alice; Leopardi, Martina Piccinni; Del Coco, Clara; Bishop, Nick