Targeted therapy for mTORC1-driven tumours through HDAC inhibition by exploiting innate vulnerability of mTORC1 hyper-activation
利用 mTORC1 过度激活的先天脆弱性,通过 HDAC 抑制对 mTORC1 驱动的肿瘤进行靶向治疗
期刊:British Journal of Cancer
影响因子:6.4
doi:10.1038/s41416-020-0839-1
Fuchun Yang, Shaogang Sun, Chenran Wang, Michael Haas, Syn Yeo, Jun-Lin Guan