日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Discovery of novel and selective GPR17 antagonists as pharmacological tools for developing new therapeutic strategies in diabetes and obesity.

发现新型选择性 GPR17 拮抗剂，作为开发糖尿病和肥胖症新治疗策略的药理学工具。

期刊:European Journal of Medicinal Chemistry
影响因子:5.9
doi:10.1016/j.ejmech.2025.117794
Zhu Hu, Conley Jason M, Karavadhi Surendra, LaVigne Justin E, Watts Val J, Sun Hongmao, Shen Min, Hall Matthew D, Ren Hongxia, Patnaik Samarjit
糖尿病
肥胖
代谢
发表日期：2025
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Identifying Molecular Properties of Ataxin-2 Inhibitors for Spinocerebellar Ataxia Type 2 Utilizing High-Throughput Screening and Machine Learning

利用高通量筛选和机器学习鉴定脊髓小脑性共济失调2型中Ataxin-2抑制剂的分子特性

期刊:Biology-Basel
影响因子:3.5
doi:10.3390/biology14050522
Sahay, Smita; Wen, Jingran; Scoles, Daniel R; Simeonov, Anton; Dexheimer, Thomas S; Jadhav, Ajit; Kales, Stephen C; Sun, Hongmao; Pulst, Stefan M; Facelli, Julio C; Jones, David E
Ataxin-2
神经科学
发表日期：2025
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Virtual Screening for the Discovery of Microbiome β-Glucuronidase Inhibitors to Alleviate Cancer Drug Toxicity.

利用虚拟筛选发现微生物组β-葡萄糖醛酸酶抑制剂以减轻癌症药物毒性

期刊:Journal of Chemical Information and Modeling
影响因子:5.3
doi:10.1021/acs.jcim.1c01414
Challa Anup P, Hu Xin, Zhang Ya-Qin, Hymes Jeffrey, Wallace Bret D, Karavadhi Surendra, Sun Hongmao, Patnaik Samarjit, Hall Matthew D, Shen Min
微生物学
发表日期：2022
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Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites

通过对疟原虫血液期和肝脏期寄生虫进行定量高通量筛选，鉴定出具有化学保护作用的抗疟药

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-021-81486-z
Dorjsuren, Dorjbal; Eastman, Richard T; Wicht, Kathryn J; Jansen, Daniel; Talley, Daniel C; Sigmon, Benjamin A; Zakharov, Alexey V; Roncal, Norma; Girvin, Andrew T; Antonova-Koch, Yevgeniya; Will, Paul M; Shah, Pranav; Sun, Hongmao; Klumpp-Thomas, Carleen; Mok, Sachel; Yeo, Tomas; Meister, Stephan; Marugan, Juan Jose; Ross, Leila S; Xu, Xin; Maloney, David J; Jadhav, Ajit; Mott, Bryan T; Sciotti, Richard J; Winzeler, Elizabeth A; Waters, Norman C; Campbell, Robert F; Huang, Wenwei; Simeonov, Anton; Fidock, David A
微生物学
发表日期：2021
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Deep Graph Learning with Property Augmentation for Predicting Drug-Induced Liver Injury

基于属性增强的深度图学习预测药物性肝损伤

期刊:Chemical Research in Toxicology
影响因子:3.8
doi:10.1021/acs.chemrestox.0c00322
Ma, Hehuan; An, Weizhi; Wang, Yuhong; Sun, Hongmao; Huang, Ruili; Huang, Junzhou
肝损伤
毒理研究
发表日期：2021
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Identification of SARS-CoV-2 viral entry inhibitors using machine learning and cell-based pseudotyped particle assay

利用机器学习和基于细胞的假病毒颗粒检测法鉴定SARS-CoV-2病毒入侵抑制剂

期刊:Bioorganic & Medicinal Chemistry
影响因子:3
doi:10.1016/j.bmc.2021.116119
Sun, Hongmao; Wang, Yuhong; Chen, Catherine Z; Xu, Miao; Guo, Hui; Itkin, Misha; Zheng, Wei; Shen, Min
微生物学
细胞生物学
SARS-CoV-2
发表日期：2021
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Retro Drug Design: From Target Properties to Molecular Structures

逆向药物设计：从靶点特性到分子结构

期刊:
影响因子:
doi:10.1101/2021.05.11.442656
Wang, Yuhong; Michael, Sam; Huang, Ruili; Zhao, Jinghua; Recabo, Katlin; Bougie, Danielle; Shu, Qiang; Shinn, Paul; Sun, Hongmao
发表日期：2021
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Prediction of hERG Liability - Using SVM Classification, Bootstrapping and Jackknifing

hERG易感性预测——基于SVM分类、自助法和刀切法

期刊:Molecular Informatics
影响因子:3.1
doi:10.1002/minf.201600126
Sun, Hongmao; Huang, Ruili; Xia, Menghang; Shahane, Sampada; Southall, Noel; Wang, Yuhong
ERG
发表日期：2017
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Synthesis and structure-activity relationship studies of N-benzyl-2-phenylpyrimidin-4-amine derivatives as potent USP1/UAF1 deubiquitinase inhibitors with anticancer activity against nonsmall cell lung cancer

合成及构效关系研究N-苄基-2-苯基嘧啶-4-胺衍生物作为强效USP1/UAF1去泛素化酶抑制剂，并研究其对非小细胞肺癌的抗癌活性

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm5010495
Dexheimer, Thomas S; Rosenthal, Andrew S; Luci, Diane K; Liang, Qin; Villamil, Mark A; Chen, Junjun; Sun, Hongmao; Kerns, Edward H; Simeonov, Anton; Jadhav, Ajit; Zhuang, Zhihao; Maloney, David J
肺癌
肿瘤
表观遗传
肿瘤免疫
泛素化
SP1
细胞生物学
发表日期：2014
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Inhibition of HERG potassium channels by domiphen bromide and didecyl dimethylammonium bromide

多米芬溴化物和二癸基二甲基溴化铵对HERG钾通道的抑制作用

期刊:European Journal of Pharmacology
影响因子:4.7
doi:10.1016/j.ejphar.2014.05.002
Long, Yan; Chen, Wanjuan; Lin, Zuoxian; Sun, Hongmao; Xia, Menghang; Zheng, Wei; Li, Zhiyuan
ERG
发表日期：2014
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