日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Linker-free PROTACs efficiently induce the degradation of oncoproteins.

无连接子的PROTACs能有效诱导癌蛋白降解

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-60107-7
Zhang Jianchao, Chen Congli, Chen Xiao, Liao Kefan, Li Fengming, Song Xiaoxiao, Liu Chaowei, Su Ming-Yuan, Sun Huiyong, Hou Tingjun, Tan Chris Soon Heng, Fang Lijing, Rao Hai
肿瘤
肿瘤免疫
发表日期：2025
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PROTAC-DB 3.0: an updated database of PROTACs with extended pharmacokinetic parameters

PROTAC-DB 3.0：包含扩展药代动力学参数的更新版 PROTAC 数据库

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkae768
Ge, Jingxuan; Li, Shimeng; Weng, Gaoqi; Wang, Huating; Fang, Meijing; Sun, Huiyong; Deng, Yafeng; Hsieh, Chang-Yu; Li, Dan; Hou, Tingjun
发表日期：2025
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Transient Cross-linking Mass Spectrometry: Taking Conformational Snapshots of Proteins

瞬态交联质谱：获取蛋白质构象快照

期刊:Analytical Chemistry
影响因子:6.7
doi:10.1021/acs.analchem.4c04939
Xie, Yuxin; Wang, Jiawen; Yang, Lei; Tao, Junjun; Xu, Yuanyuan; Hu, Yang; Zou, Guiqing; Su, Yu; Liu, Meijun; Sun, Huiyong; Hao, Haiping; Xu, Xiaowei; Zheng, Qiuling
发表日期：2025
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Uncovering the Kinetic Characteristics and Degradation Preference of PROTAC Systems with Advanced Theoretical Analyses

利用先进的理论分析揭示PROTAC体系的动力学特性和降解偏好

期刊:JACS Au
影响因子:8.7
doi:10.1021/jacsau.3c00195
Tang, Rongfan; Wang, Zhe; Xiang, Sutong; Wang, Lingling; Yu, Yang; Wang, Qinghua; Deng, Qirui; Hou, Tingjun; Sun, Huiyong
发表日期：2023
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Deciphering the Shared and Specific Drug Resistance Mechanisms of Anaplastic Lymphoma Kinase via Binding Free Energy Computation

通过结合自由能计算解析间变性淋巴瘤激酶的共有和特异性耐药机制

期刊:
影响因子:
doi:10.34133/research.0170
Yu, Yang; Wang, Zhe; Wang, Lingling; Wang, Qinghua; Tang, Rongfan; Xiang, Sutong; Deng, Qirui; Hou, Tingjun; Sun, Huiyong
淋巴瘤
信号转导
发表日期：2023
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Predicting the mutation effects of protein-ligand interactions via end-point binding free energy calculations: strategies and analyses

通过终点结合自由能计算预测蛋白质-配体相互作用的突变效应：策略与分析

期刊:Journal of Cheminformatics
影响因子:5.7
doi:10.1186/s13321-022-00639-y
Yu, Yang; Wang, Zhe; Wang, Lingling; Tian, Sheng; Hou, Tingjun; Sun, Huiyong
发表日期：2022
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Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays

通过基于结构的虚拟筛选和生物测定发现新型雄激素受体配体

期刊:Genomics Proteomics & Bioinformatics
影响因子:7.9
doi:10.1016/j.gpb.2018.03.007
Zhou, Wenfang; Duan, Mojie; Fu, Weitao; Pang, Jinping; Tang, Qin; Sun, Huiyong; Xu, Lei; Chang, Shan; Li, Dan; Hou, Tingjun
信号转导
免疫/内分泌
发表日期：2018
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Molecular Dynamics Simulations Revealed the Regulation of Ligands to the Interactions between Androgen Receptor and Its Coactivator

分子动力学模拟揭示了配体对雄激素受体及其共激活因子相互作用的调控作用

期刊:Journal of Chemical Information and Modeling
影响因子:5.3
doi:10.1021/acs.jcim.8b00283
Liu, Na; Zhou, Wenfang; Guo, Yue; Wang, Junmei; Fu, Weitao; Sun, Huiyong; Li, Dan; Duan, Mojie; Hou, Tingjun
信号转导
免疫/内分泌
发表日期：2018
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Assessing the performance of MM/PBSA and MM/GBSA methods. 8. Predicting binding free energies and poses of protein-RNA complexes

评估 MM/PBSA 和 MM/GBSA 方法的性能。8. 预测蛋白质-RNA 复合物的结合自由能和构象

期刊:RNA
影响因子:5
doi:10.1261/rna.065896.118
Chen, Fu; Sun, Huiyong; Wang, Junmei; Zhu, Feng; Liu, Hui; Wang, Zhe; Lei, Tailong; Li, Youyong; Hou, Tingjun
多发性骨髓瘤
发表日期：2018
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Fullerene derivatives act as inhibitors of leukocyte common antigen based on molecular dynamics simulations

基于分子动力学模拟，富勒烯衍生物可作为白细胞共同抗原的抑制剂。

期刊:RSC Advances
影响因子:4.6
doi:10.1039/c7ra13543b
Yu, Yi; Sun, Huiyong; Hou, Tingjun; Wang, Suidong; Li, Youyong
细胞生物学
发表日期：2018
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