Sun Xiaoou相关文献与解析，生知库 | 链接生命科学的每一步

METTL7B-stabilized lncRNA-MIR22HG to drive p53-mediated neuronal apoptosis via the ubiquitinating JARID2 in cerebral ischemia/reperfusion injury.

METTL7B 稳定的 lncRNA-MIR22HG 通过泛素化的 JARID2 驱动 p53 介导的神经元凋亡，从而导致脑缺血/再灌注损伤。

期刊:Cell Biology and Toxicology

影响因子:5.9

doi:10.1007/s10565-026-10157-4

Zhang Hao, Li Meng, Wu Yilin, Sun Xiaoou

Upregulated ARMCX1 suppresses nasopharyngeal carcinoma progression by promoting TRIM21-mediated β-catenin degradation

ARMCX1 上调通过促进 TRIM21 介导的 β-catenin 降解来抑制鼻咽癌的进展。

期刊:Cellular Oncology

影响因子:4.8

doi:10.1007/s13402-025-01161-7

Hu, Zhe; Zhuo, Enqing; Guo, Jiankang; Wu, Yilin; Sun, Xiaoou; Qiu, Houkuang; Zhou, Yangfan; Tan, Xi; Zhang, Xuhui

Structural insight into the self-activation and G-protein coupling of P2Y2 receptor.

P2Y2受体的自身激活和G蛋白偶联的结构解析

期刊:Cell Discovery

影响因子:12.5

doi:10.1038/s41421-025-00797-x

Lan Baoliang, Zhang Shuhao, Chen Kai, Dai Shengjie, Fei Jiaqi, Gao Kaixuan, Sun Xiaoou, Lin Bin, Liu Xiangyu

免疫/内分泌

发表日期：2025

文献求助收藏

Extracellular nanobody screening using conformationally stable GPCR variants

利用构象稳定的GPCR变体进行细胞外纳米抗体筛选

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2508879122

Zhang, Xin; Gao, Kaixuan; Nie, Jia; Meng, Hengyu; Sun, Xiaoou; Zhao, Jiawei; Liu, Xiangyu

Molecular mechanism of human Î±(1A)-adrenoceptor inhibition by Mamba snake toxin AdTx1.

曼巴蛇毒素AdTx1抑制人类α(1A)-肾上腺素受体的分子机制

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-025-08405-0

Shi Mingyu, Zhang Shuhao, Zhu Angqi, Toyoda Yosuke, Kong Fang, Sun Xiaoou, Xu Xinyu, Yan Chuangye, Liu Xiangyu

Identification of SURF4 and RALGAPA1 as promising therapeutic targets in glioblastoma and pan-cancer through integrative multi-omics, CRISPR-Cas9 screening and prognostic meta-analysis.

通过整合多组学、CRISPR-Cas9 筛选和预后荟萃分析，确定 SURF4 和 RALGAPA1 为胶质母细胞瘤和泛癌的潜在治疗靶点

期刊:Cancer Immunology Immunotherapy

影响因子:5.1

doi:10.1007/s00262-025-04034-y

Wang Fei, Chen Yuxuan, Huang Run, Lu Dengfeng, Zhang Juyi, Yang Yanbo, Dang Hanhan, Liu Meirong, Chen Zhouqing, Sun Xiaoou, Wang Zhong

Long Non-Coding RNA 1810026B05Rik Mediates Cerebral Ischemia/Reperfusion-Induced Neuronal Injury Through NF-ÎºB Pathway Activation.

长链非编码RNA 1810026B05Rik通过NF-κB通路激活介导脑缺血/再灌注诱导的神经元损伤。

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26199756

Zhang Hao, Li Meng, Yao Jiayu, Jiang Xuan, Feng Junxiao, Shi Xingjuan, Sun Xiaoou

神经科学

发表日期：2025

文献求助收藏

METTL3-Driven m6A Epigenetic Remodeling of lncRNA-AU020206 Stabilizes SLC7A11 via YTHDC2 Attenuates Apoptosis and Ferroptosis in Cerebral Ischemia/Reperfusion Injury

METTL3驱动的lncRNA-AU020206的m6A表观遗传重塑通过YTHDC2稳定SLC7A11，从而减轻脑缺血/再灌注损伤中的细胞凋亡和铁死亡

期刊:Biomolecules

影响因子:4.8

doi:10.3390/biom15101353

Zhang, Hao; Guan, Yajin; Li, Meng; Wu, Yilin; Sun, Xiaoou

Comprehensive analysis reveals cholesterol metabolism-related signature for predicting prognosis and guiding individualized treatment of glioma

综合分析揭示了与胆固醇代谢相关的特征，可用于预测胶质瘤的预后并指导个体化治疗。

期刊:Heliyon

影响因子:3.6

doi:10.1016/j.heliyon.2024.e41601

Lu, Dengfeng; Wang, Fei; Yang, Yayi; Duan, Aojie; Ren, Yubo; Feng, Yun; Teng, Haiying; Chen, Zhouqing; Sun, Xiaoou; Wang, Zhong

Extrachromosomal circular DNA: a potential clinical therapeutic target in malignant tumors

染色体外环状DNA：恶性肿瘤潜在的临床治疗靶点

METTL7B-stabilized lncRNA-MIR22HG to drive p53-mediated neuronal apoptosis via the ubiquitinating JARID2 in cerebral ischemia/reperfusion injury.

METTL7B 稳定的 lncRNA-MIR22HG 通过泛素化的 JARID2 驱动 p53 介导的神经元凋亡，从而导致脑缺血/再灌注损伤。

Upregulated ARMCX1 suppresses nasopharyngeal carcinoma progression by promoting TRIM21-mediated β-catenin degradation

ARMCX1 上调通过促进 TRIM21 介导的 β-catenin 降解来抑制鼻咽癌的进展。

Structural insight into the self-activation and G-protein coupling of P2Y2 receptor.

P2Y2受体的自身激活和G蛋白偶联的结构解析

Extracellular nanobody screening using conformationally stable GPCR variants

利用构象稳定的GPCR变体进行细胞外纳米抗体筛选

Molecular mechanism of human Î±(1A)-adrenoceptor inhibition by Mamba snake toxin AdTx1.

曼巴蛇毒素AdTx1抑制人类α(1A)-肾上腺素受体的分子机制

Identification of SURF4 and RALGAPA1 as promising therapeutic targets in glioblastoma and pan-cancer through integrative multi-omics, CRISPR-Cas9 screening and prognostic meta-analysis.

通过整合多组学、CRISPR-Cas9 筛选和预后荟萃分析，确定 SURF4 和 RALGAPA1 为胶质母细胞瘤和泛癌的潜在治疗靶点

Long Non-Coding RNA 1810026B05Rik Mediates Cerebral Ischemia/Reperfusion-Induced Neuronal Injury Through NF-ÎºB Pathway Activation.

长链非编码RNA 1810026B05Rik通过NF-κB通路激活介导脑缺血/再灌注诱导的神经元损伤。

METTL3-Driven m6A Epigenetic Remodeling of lncRNA-AU020206 Stabilizes SLC7A11 via YTHDC2 Attenuates Apoptosis and Ferroptosis in Cerebral Ischemia/Reperfusion Injury

METTL3驱动的lncRNA-AU020206的m6A表观遗传重塑通过YTHDC2稳定SLC7A11，从而减轻脑缺血/再灌注损伤中的细胞凋亡和铁死亡

Comprehensive analysis reveals cholesterol metabolism-related signature for predicting prognosis and guiding individualized treatment of glioma

综合分析揭示了与胆固醇代谢相关的特征，可用于预测胶质瘤的预后并指导个体化治疗。