日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mitochondrial fission produces a Warburg effect via the oxidative inhibition of prolyl hydroxylase domain-2

线粒体分裂通过氧化抑制脯氨酰羟化酶结构域-2产生瓦博格效应。

Sun, Xutong; Yegambaram, Manivannan; Lu, Qing; Garcia Flores, Alejandro E; Pokharel, Marissa D; Soto, Jamie; Aggarwal, Saurabh; Wang, Ting; Fineman, Jeffrey R; Black, Stephen M

Multi-omics integration reveals the impact of mediterranean diet on hepatic metabolism and gut microbiota in mice with metabolic dysfunction-associated steatotic liver disease

多组学整合揭示了地中海饮食对代谢功能障碍相关脂肪肝小鼠肝脏代谢和肠道菌群的影响

Wang, Zixuan; Chen, Ge; Sun, Xutong; Xiao, Jia; Kong, Lingling; Jiang, Shunshun; Xu, Tingting; Wang, Meijiao; Zhao, Hong

Chloroquine Restores eNOS Signaling in Shunt Endothelial Cells via Inhibiting eNOS Uncoupling

氯喹通过抑制eNOS解偶联恢复分流内皮细胞中的eNOS信号传导

Liang, Ying; Ornatowski, Wojciech; Lu, Qing; Sun, Xutong; Yegambaram, Manivannan; Feng, Anlin; Dong, Yishu; Aggarwal, Saurabh; Unwalla, Hoshang J; Fineman, Jeffrey R; Black, Stephen M; Wang, Ting

Mechanotransductive stabilization of HIF-1α is inhibited by mitochondrial antioxidant therapy in the setting of pulmonary overcirculation.

在肺循环过度的情况下,线粒体抗氧化疗法会抑制 HIF-1α 的机械转导稳定作用

Boehme Jason T, Datar Sanjeev A, Sun Xutong, Gong Wenhui, Lu Qing, Soto Jamie, Smith Michael A, Garcia-Flores Alejandro E, Raff Gary W, Wang Ting, Maltepe Emin, Black Stephen M, Fineman Jeffrey R

c-Myc promotes metabolic reprogramming in pulmonary hypertension via the stimulation of glutaminolysis and the reductive tricarboxylic acid cycle

c-Myc通过刺激谷氨酰胺分解和还原性三羧酸循环,促进肺动脉高压中的代谢重编程。

Yegambaram, Manivannan; Sun, Xutong; Lu, Qing; Flores, Alejandro Garcia; Zemskova, Marina; Soto, Jamie; Rauckhorst, Adam; Maltepe, Emin; Wang, Ting; Fineman, Jeffrey R; Black, Stephen M

Mitochondrial hyperfusion induces metabolic remodeling in lung endothelial cells by modifying the activities of electron transport chain complexes I and III

线粒体过度融合通过改变电子传递链复合物 I 和 III 的活性,诱导肺内皮细胞代谢重塑。

Yegambaram, Manivannan; Sun, Xutong; Lu, Qing; Jin, Yan; Ornatowski, Wojciech; Soto, Jamie; Aggarwal, Saurabh; Wang, Ting; Tieu, Kim; Gu, Haiwei; Fineman, Jeffrey R; Black, Stephen M

Inflammatory lung injury is associated with endothelial cell mitochondrial fission and requires the nitration of RhoA and cytoskeletal remodeling.

炎症性肺损伤与内皮细胞线粒体分裂有关,需要 RhoA 硝化和细胞骨架重塑

Pokharel Marissa D, Fu Panfeng, Garcia-Flores Alejandro, Yegambaram Manivannan, Lu Qing, Sun Xutong, Unwalla Hoshang, Aggarwal Saurabh, Fineman Jeffrey R, Wang Ting, Black Stephen M

Simvastatin restores pulmonary endothelial function in the setting of pulmonary over-circulation

辛伐他汀可恢复肺循环过度时的肺内皮功能

Boehme, Jason T; Sun, Xutong; Lu, Qing; Barton, Jubilee; Wu, Xiaomin; Gong, Wenhui; Raff, Gary W; Datar, Sanjeev A; Wang, Ting; Fineman, Jeffrey R; Black, Stephen M

LncRNA PVT1 facilitates the growth and metastasis of colorectal cancer by sponging with miR-3619-5p to regulate TRIM29 expression

LncRNA PVT1通过与miR-3619-5p相互作用调控TRIM29表达促进结直肠癌的生长和转移

Zhenni Sun, Xutong Li, Yanyan Shi, Yasai Yao

Ovine Models of Congenital Heart Disease and the Consequences of Hemodynamic Alterations for Pulmonary Artery Remodeling

绵羊先天性心脏病模型及血流动力学改变对肺动脉重塑的影响

Johnson Kameny, Rebecca; Datar, Sanjeev A; Boehme, Jason B; Morris, Catherine; Zhu, Terry; Goudy, Brian D; Johnson, Eric G; Galambos, Csaba; Raff, Gary W; Sun, Xutong; Wang, Ting; Chiacchia, Samuel R; Lu, Qing; Black, Stephen M; Maltepe, Emin; Fineman, Jeffrey R