日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rational design and synthesis of non-competitive transcription inhibitors targeting a conserved RNA polymerase-σ (A) interface

合理设计并合成靶向保守的RNA聚合酶-σ(A)界面的非竞争性转录抑制剂

Tandi, Mukesh; Hati, Nilima; Kore, Mukul; Behera, Debashree; Patel, Twinkal; Eeba; Agarwal, Nisheeth; Gopal, Balasubramanian; Sundriyal, Sandeep

S-nitrosylation of EZH2 alters PRC2 assembly, methyltransferase activity, and EZH2 stability to maintain endothelial homeostasis.

EZH2 的 S-亚硝基化会改变 PRC2 的组装、甲基转移酶活性和 EZH2 的稳定性,从而维持内皮细胞的稳态

Sakhuja Ashima, Bhattacharyya Ritobrata, Katakia Yash Tushar, Ramakrishnan Shyam Kumar, Chakraborty Srinjoy, Jayakumar Hariharan, Tripathi Shailesh Mani, Pandya Thakkar Niyati, Thakar Sumukh, Sundriyal Sandeep, Chowdhury Shibasish, Majumder Syamantak

Multicomponent reactions (MCRs) yielding medicinally relevant rings: a recent update and chemical space analysis of the scaffolds

多组分反应(MCRs)生成具有药用价值的环状化合物:最新进展及骨架化学空间分析

Tandi, Mukesh; Sharma, Vaibhav; Gopal, Balasubramanian; Sundriyal, Sandeep

Development and experimental validation of a machine learning model for the prediction of new antimalarials.

开发和实验验证用于预测新型抗疟疾药物的机器学习模型

Kore Mukul, Acharya Dimple, Sharma Lakshya, Vembar Shruthi Sridhar, Sundriyal Sandeep

Basic nitrogen (BaN): a 'privileged element' in medicinal chemistry

碱性氮(BaN):药物化学中的“特权元素”

Sundriyal, Sandeep

Physicochemical Profiling and Comparison of Research Antiplasmodials and Advanced Stage Antimalarials with Oral Drugs

研究用抗疟药和晚期抗疟药与口服药物的理化性质分析及比较

Bhanot, Amritansh; Sundriyal, Sandeep

Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans

组蛋白甲基转移酶抑制剂是口服生物利用度高、起效迅速的分子,对引起人类疟疾的不同疟原虫种类均有活性。

Malmquist, Nicholas A; Sundriyal, Sandeep; Caron, Joachim; Chen, Patty; Witkowski, Benoit; Menard, Didier; Suwanarusk, Rossarin; Renia, Laurent; Nosten, Francois; Jiménez-Díaz, María Belén; Angulo-Barturen, Iñigo; Santos Martínez, María; Ferrer, Santiago; Sanz, Laura M; Gamo, Francisco-Javier; Wittlin, Sergio; Duffy, Sandra; Avery, Vicky M; Ruecker, Andrea; Delves, Michael J; Sinden, Robert E; Fuchter, Matthew J; Scherf, Artur

Identification of 2,4-diamino-6,7-dimethoxyquinoline derivatives as G9a inhibitors†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4md00274a

鉴定出 2,4-二氨基-6,7-二甲氧基喹啉衍生物为 G9a 抑制剂†电子补充信息 (ESI) 可用。参见 DOI:10.1039/c4md00274a

Srimongkolpithak, Nitipol; Sundriyal, Sandeep; Li, Fengling; Vedadi, Masoud; Fuchter, Matthew J

2-Substituted 4,5-dihydrothiazole-4-carboxylic acids are novel inhibitors of metallo-β-lactamases

2-取代的4,5-二氢噻唑-4-羧酸是新型金属β-内酰胺酶抑制剂

Chen, Pinhong; Horton, Lori B; Mikulski, Rose L; Deng, Lisheng; Sundriyal, Sandeep; Palzkill, Timothy; Song, Yongcheng

Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii

弓形虫顶质体异戊二烯前体合成及磷霉素抗性的分子基础

Nair, Sethu C; Brooks, Carrie F; Goodman, Christopher D; Sturm, Angelika; McFadden, Geoffrey I; Sundriyal, Sandeep; Anglin, Justin L; Song, Yongcheng; Moreno, Silvia N J; Striepen, Boris