Novel anti-CD73-IL-2v bispecific fusion protein augments antitumor immunity by alleviating immunosuppressive adenosine pathways in CD8(+) T cells
新型抗CD73-IL-2v双特异性融合蛋白通过缓解CD8(+) T细胞中的免疫抑制性腺苷通路来增强抗肿瘤免疫力。
期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2023-008594
Shin, Kayoung; Park, Min; Kim, Seoho; Lee, Haejong; Lee, Yuseong; Kim, Jongil; Park, Suyoun; Kim, Jisoo; Lee, Kyungwha; Park, Chong Woo; Kim, Ji-Hyun; Lee, Eun-Jin; Mok, Hyuckjun; Oh, Sung-Man; Lee, Sanghee; Oh, Young Min; Lee, Wonjae; Shim, Yaein Amy; Cho, Young-Gyu; Park, Junsik; Lee, Jung-Yun; Koh, Young Jun; Kim, Kook Hwan; Jang, Myoung Ho
肿瘤
CD7
T细胞
肿瘤免疫
信号转导
CD73
CD8
T细胞
IL-2
细胞生物学
免疫/内分泌
