日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The bactericidal FabI inhibitor Debio 1453 clears antibiotic-resistant Neisseria gonorrhoeae infection in vivo

杀菌性FabI抑制剂Debio 1453可在体内清除耐抗生素的淋病奈瑟菌感染。

Gerusz, Vincent; Regenass, Pierre; Rousseau, Quentin; Moraine, Victor; Dao, Justine; Lavé, Xavier; Das, Shampa; Hue Perron, Josée; Fajas Descamps, Laurence; Bravo, Juan; Dieppois, Guennaëlle; Kaplan, Nachum; Lefebre, Matthew; Altomari, Deanna; Romanov, Vladimir; Finn, Terry; Daram, Pierre; Bernardini, Francesca; Gross, Michaël; Lysek, Robert; Adam, Aurélien; Pohin, Danig; Maio, Maurizio; Tatsis, Vasileios; Sunose, Mihiro; Ronin, Céline; Ciesielski, Fabrice; Ahlstrand, Josefine; Jacobsson, Susanne; Unemo, Magnus; Cameron, David R

Structure-activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling

通过比较转录组分析和分子建模探究 G-四链体靶向实验药物 QN-302 及其两种类似物的构效关系

Ahmed Abdullah Ahmed, Shuang Chen, Maria Roman-Escorza, Richard Angell, Sally Oxenford, Matthew McConville, Naomi Barton, Mihiro Sunose, Dan Neidle, Shozeb Haider, Tariq Arshad, Stephen Neidle

Neutrophil infiltration in co-housed littermates plays a key role in nasal transmission of Streptococcus pneumoniae in an infant mouse model

在幼鼠模型中,同窝幼鼠的中性粒细胞浸润在肺炎链球菌的鼻腔传播中起着关键作用

Fumie Kaneko, Masamitsu Kono, Hiroshi Sunose, Muneki Hotomi

In Vitro and In Vivo Efficacy of a Novel and Long-Acting Fungicidal Azole, PC1244, on Aspergillus fumigatus Infection

新型长效杀菌唑 PC1244 对烟曲霉感染的体外和体内疗效

Thomas Colley #, Gurpreet Sehra #, Anuradha Chowdhary, Alexandre Alanio, Steven L Kelly, Yasuo Kizawa, Darius Armstrong-James, Matthew C Fisher, Andrew G S Warrilow, Josie E Parker, Diane E Kelly, Genki Kimura, Yuki Nishimoto, Mihiro Sunose, Stuart Onions, Damien Crepin, Franz Lagasse, Matthew Critt

In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection

新型长效吸入唑 PC945 对烟曲霉感染的体外和体内抗真菌特性

Thomas Colley, Alexandre Alanio, Steven L Kelly, Gurpreet Sehra, Yasuo Kizawa, Andrew G S Warrilow, Josie E Parker, Diane E Kelly, Genki Kimura, Lauren Anderson-Dring, Takahiro Nakaoki, Mihiro Sunose, Stuart Onions, Damien Crepin, Franz Lagasse, Matthew Crittall, Jonathan Shannon, Michael Cooke, Sté

High Fractional Occupancy of a Tandem Maf Recognition Element and Its Role in Long-Range β-Globin Gene Regulation

串联 Maf 识别元件的高分数占有率及其在长距离 β-珠蛋白基因调控中的作用

Jared R Stees, Mir A Hossain, Tomoki Sunose, Yasushi Kudo, Carolina E Pardo, Nancy H Nabilsi, Russell P Darst, Rosha Poudyal, Kazuhiko Igarashi, Suming Huang, Michael P Kladde, Jörg Bungert

Embryonal sarcoma of the liver with chondroid differentiation

肝脏胚胎性肉瘤伴软骨样分化

Kinjo, Sawako; Sakurai, Shinji; Hirato, Junko; Sunose, Yutaka