日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Variably protease-sensitive prionopathy: mass spectrometry analysis of the pathogenic prion protein provides a new perspective

对蛋白酶敏感性可变的朊病毒病:致病性朊病毒蛋白的质谱分析提供了一种新的视角

Nemani, S K; Xiao, X; Notari, S; Cali, I; Lundberg, K; Cracco, L; Appleby, B S; Surewicz, W K; Sim, V L; Gambetti, P

Structural exposure of different microtubule binding domains determines the propagation and toxicity of pathogenic tau conformers in Alzheimer's disease.

不同微管结合域的结构暴露决定了阿尔茨海默病中致病性 tau 构象体的传播和毒性

Hromadkova Lenka, Kim Chae, Haldiman Tracy, Siddiqi Mohammad Khursheed, Surewicz Krystyna, Urquhart Kiley, Sadruddin Dur-E-Nayab, Peng Lihua, Zhu Xiongwei, Surewicz Witold K, Cohen Mark L, Chance Mark R, de Silva Rohan, Kiselar Janna, Safar Jiri G

Distinct liquid-liquid phase separation properties of end-binding proteins EB1 and EB3

末端结合蛋白EB1和EB3具有不同的液-液相分离特性

Boyko, Solomiia; Li, Qiuye; Surewicz, Krystyna; Surewicz, Witold K

Pathological C-terminal phosphomimetic substitutions alter the mechanism of liquid-liquid phase separation of TDP-43 low complexity domain

病理性C端磷酸模拟取代改变了TDP-43低复杂度结构域的液-液相分离机制

Haider, Raza; Shipley, Brandon; Surewicz, Krystyna; Hinczewski, Michael; Surewicz, Witold K

Phosphomimetic substitutions in TDP-43's transiently α-helical region suppress phase separation

TDP-43瞬时α螺旋区域中的磷酸化修饰可抑制相分离

Haider, Raza; Penumutchu, Srinivasa; Boyko, Solomiia; Surewicz, Witold K

Copper binding alters the core structure of amyloid fibrils formed by Y145Stop human prion protein

铜结合会改变由Y145Stop人朊病毒蛋白形成的淀粉样原纤维的核心结构。

Sridharan, Vidhyalakshmi; George, Tara; Conroy, Daniel W; Shaffer, Zach; Surewicz, Witold K; Jaroniec, Christopher P

Tau liquid-liquid phase separation in neurodegenerative diseases

神经退行性疾病中的Tau蛋白液-液相分离

Boyko, Solomiia; Surewicz, Witold K

Cryo-EM structure of disease-related prion fibrils provides insights into seeding barriers

疾病相关朊病毒原纤维的冷冻电镜结构为种子屏障的形成提供了新的见解

Li, Qiuye; Jaroniec, Christopher P; Surewicz, Witold K

Influence of the Dynamically Disordered N-Terminal Tail Domain on the Amyloid Core Structure of Human Y145Stop Prion Protein Fibrils

动态无序的N端尾部结构域对人类Y145Stop朊病毒蛋白原纤维淀粉样核心结构的影响

Qi, Zhe; Surewicz, Krystyna; Surewicz, Witold K; Jaroniec, Christopher P

(13)C and (15)N chemical shift assignments of A117V and M129V human Y145Stop prion protein amyloid fibrils

(13)C 和(15)N 化学位移归属 A117V 和 M129V 人类 Y145Stop 朊病毒蛋白淀粉样原纤维

Dao, Hanh H; Hlaing, May Z; Ma, Yixuan; Surewicz, Krystyna; Surewicz, Witold K; Jaroniec, Christopher P