日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A robust and flexible baculovirus-insect cell system for AAV vector production with improved yield, capsid ratios and potency

一种稳健灵活的杆状病毒-昆虫细胞系统,用于生产AAV载体,可提高产量、衣壳比例和效力。

Marwidi, Yoko; Nguyen, Hoang-Oanh B; Santos, David; Wangzor, Tenzin; Bhardwaj, Sumita; Ernie, Gabriel; Prawdzik, Gregg; Lew, Garrett; Shivak, David; Trias, Michael; Padilla, Jada; Tran, Hung; Meyer, Kathleen; Surosky, Richard; Ward, Alex Michael

Persistent repression of tau in the brain using engineered zinc finger protein transcription factors

利用工程化锌指蛋白转录因子持续抑制大脑中的tau蛋白

Susanne Wegmann ,Sarah L DeVos ,Bryan Zeitler ,Kimberly Marlen ,Rachel E Bennett ,Marta Perez-Rando ,Danny MacKenzie ,Qi Yu ,Caitlin Commins ,Riley N Bannon ,Bianca T Corjuc ,Alison Chase ,Lisa Diez ,Hoang-Oanh B Nguyen ,Sarah Hinkley ,Lei Zhang ,Alicia Goodwin ,Annemarie Ledeboer ,Stephen Lam ,Irina Ankoudinova ,Hung Tran ,Nicholas Scarlott ,Rainier Amora ,Richard Surosky ,Jeffrey C Miller ,Ashley B Robbins ,Edward J Rebar ,Fyodor D Urnov ,Michael C Holmes ,Amy M Pooler ,Brigit Riley ,H Steve Zhang ,Bradley T Hyman

Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors

使用 ZFN mRNA 和 AAV6 供体在造血干细胞和祖细胞中进行同源性驱动的基因组编辑

Jianbin Wang, Colin M Exline, Joshua J DeClercq, G Nicholas Llewellyn, Samuel B Hayward, Patrick Wai-Lun Li, David A Shivak, Richard T Surosky, Philip D Gregory, Michael C Holmes, Paula M Cannon

Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV

对 HIV 感染者自体 CD4 T 细胞中的 CCR5 进行基因编辑

Tebas, Pablo; Stein, David; Tang, Winson W; Frank, Ian; Wang, Shelley Q; Lee, Gary; Spratt, S Kaye; Surosky, Richard T; Giedlin, Martin A; Nichol, Geoff; Holmes, Michael C; Gregory, Philip D; Ando, Dale G; Kalos, Michael; Collman, Ronald G; Binder-Scholl, Gwendolyn; Plesa, Gabriela; Hwang, Wei-Ting; Levine, Bruce L; June, Carl H

Manufacturing and characterization of a recombinant adeno-associated virus type 8 reference standard material

重组腺相关病毒8型参考标准物质的制备和表征

Ayuso, Eduard; Blouin, Véronique; Lock, Martin; McGorray, Susan; Leon, Xavier; Alvira, Mauricio R; Auricchio, Alberto; Bucher, Stephanie; Chtarto, Abdelwahed; Clark, K Reed; Darmon, Christophe; Doria, Monica; Fountain, Will; Gao, Guangping; Gao, Kai; Giacca, Mauro; Kleinschmidt, Juergen; Leuchs, Barbara; Melas, Catherine; Mizukami, Hiroaki; Müller, Marcus; Noordman, Yvet; Bockstael, Olivier; Ozawa, Keiya; Pythoud, Catherine; Sumaroka, Marina; Surosky, Richard; Tenenbaum, Liliane; van der Linden, Inge; Weins, Brigitte; Wright, J Fraser; Zhang, Xinhua; Zentilin, Lorena; Bosch, Fatima; Snyder, Richard O; Moullier, Philippe

Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material

重组腺相关病毒2型参考标准物质的特性分析

Lock, Martin; McGorray, Susan; Auricchio, Alberto; Ayuso, Eduard; Beecham, E Jeffrey; Blouin-Tavel, Véronique; Bosch, Fatima; Bose, Mahuya; Byrne, Barry J; Caton, Tina; Chiorini, John A; Chtarto, Abdelwahed; Clark, K Reed; Conlon, Thomas; Darmon, Christophe; Doria, Monica; Douar, Anne; Flotte, Terence R; Francis, Joyce D; Francois, Achille; Giacca, Mauro; Korn, Michael T; Korytov, Irina; Leon, Xavier; Leuchs, Barbara; Lux, Gabriele; Melas, Catherine; Mizukami, Hiroaki; Moullier, Philippe; Müller, Marcus; Ozawa, Keiya; Philipsberg, Tina; Poulard, Karine; Raupp, Christina; Rivière, Christel; Roosendaal, Sigrid D; Samulski, R Jude; Soltys, Steven M; Surosky, Richard; Tenenbaum, Liliane; Thomas, Darby L; van Montfort, Bart; Veres, Gabor; Wright, J Fraser; Xu, Yili; Zelenaia, Olga; Zentilin, Lorena; Snyder, Richard O

Mutations on the external surfaces of adeno-associated virus type 2 capsids that affect transduction and neutralization

影响转导和中和的腺相关病毒2型衣壳外表面突变

Lochrie, Michael A; Tatsuno, Gwen P; Christie, Brian; McDonnell, Jennifer Wellman; Zhou, Shangzhen; Surosky, Richard; Pierce, Glenn F; Colosi, Peter

Charged-to-alanine scanning mutagenesis of the N-terminal half of adeno-associated virus type 2 Rep78 protein

腺相关病毒2型Rep78蛋白N端半段的带电荷丙氨酸扫描诱变

Urabe, M; Hasumi, Y; Kume, A; Surosky, R T; Kurtzman, G J; Tobita, K; Ozawa, K

Adeno-associated virus Rep proteins target DNA sequences to a unique locus in the human genome

腺相关病毒的Rep蛋白将DNA序列靶向人类基因组中的一个独特位点。

Surosky, R T; Urabe, M; Godwin, S G; McQuiston, S A; Kurtzman, G J; Ozawa, K; Natsoulis, G

Meiotic disjunction of homologs in Saccharomyces cerevisiae is directed by pairing and recombination of the chromosome arms but not by pairing of the centromeres

酿酒酵母中同源染色体的减数分裂分离是由染色体臂的配对和重组决定的,而不是由着丝粒的配对决定的。

Surosky, R T; Tye, B K