An open label study of the safety and efficacy of a single dose of weekly chloroquine and azithromycin administered for malaria prophylaxis in healthy adults challenged with 7G8 chloroquine-resistant Plasmodium falciparum in a controlled human malaria infection model
一项开放标签研究,旨在评估每周一次单剂量氯喹和阿奇霉素用于预防疟疾的安全性和有效性,研究对象为在受控的人类疟疾感染模型中感染7G8氯喹耐药恶性疟原虫的健康成年人。
期刊:Malaria Journal
影响因子:3
doi:10.1186/s12936-020-03409-z
Livezey, Jeffrey; Twomey, Patrick; Morrison, Meshell; Cicatelli, Susan; Duncan, Elizabeth H; Hamer, Melinda; Lee, Christine; Hutter, Jack; Mills, Kristin; DeLuca, Jesse; Poon, Lucas; Selig, Daniel; Vuong, Chau; Sousa, Jason; Oliver, Thomas; Bennett, Jason; Moon, James E; Sikaffy, April; Sedegah, Martha; Tosh, Donna; Kreishman-Deitrick, Mara; Waterman, Paige