日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Selective inhibition of the p38α MAPK-MK2 axis inhibits inflammatory cues including inflammasome priming signals

选择性抑制 p38α MAPK-MK2 轴可抑制炎症信号,包括炎症小体启动信号

Chun Wang, Susan Hockerman, E Jon Jacobsen, Yael Alippe, Shaun R Selness, Heidi R Hope, Jeffrey L Hirsch, Stephen J Mnich, Matthew J Saabye, William F Hood, Sheri L Bonar, Yousef Abu-Amer, Ariela Haimovich, Hal M Hoffman, Joseph B Monahan, Gabriel Mbalaviele

Orally active MMP-1 sparing α-tetrahydropyranyl and α-piperidinyl sulfone matrix metalloproteinase (MMP) inhibitors with efficacy in cancer, arthritis, and cardiovascular disease

口服活性 MMP-1 保留 α-四氢吡喃基和 α-哌啶基砜基质金属蛋白酶 (MMP) 抑制剂,可有效治疗癌症、关节炎和心血管疾病

Daniel P Becker, Thomas E Barta, Louis J Bedell, Terri L Boehm, Brian R Bond, Jeffery Carroll, Chris P Carron, Gary A Decrescenzo, Alan M Easton, John N Freskos, Chris L Funckes-Shippy, Marcia Heron, Susan Hockerman, Carol Pearcy Howard, James R Kiefer, Madeleine H Li, Karl J Mathis, Joseph J McDona