Single-Dose Intranasal Administration of AdCOVID Elicits Systemic and Mucosal Immunity against SARS-CoV-2 and Fully Protects Mice from Lethal Challenge
单剂量鼻内给药AdCOVID可诱导针对SARS-CoV-2的全身性和黏膜免疫,并完全保护小鼠免受致命攻击。
期刊:Vaccines
影响因子:3.4
doi:10.3390/vaccines9080881
King, R Glenn; Silva-Sanchez, Aaron; Peel, Jessica N; Botta, Davide; Dickson, Alexandria M; Pinto, Amelia K; Meza-Perez, Selene; Allie, S Rameeza; Schultz, Michael D; Liu, Mingyong; Bradley, John E; Qiu, Shihong; Yang, Guang; Zhou, Fen; Zumaquero, Esther; Simpler, Thomas S; Mousseau, Betty; Killian, John T Jr; Dean, Brittany; Shang, Qiao; Tipper, Jennifer L; Risley, Christopher A; Harrod, Kevin S; Feng, Tsungwei; Lee, Young; Shiberu, Bethlehem; Krishnan, Vyjayanthi; Peguillet, Isabelle; Zhang, Jianfeng; Green, Todd J; Randall, Troy D; Suschak, John J; Georges, Bertrand; Brien, James D; Lund, Frances E; Roberts, M Scot