Agomelatine Mitigates Kidney Damage in Obese Insulin-Resistant Rats by Inhibiting Inflammation and Necroptosis via the TNF-α/NF-ĸB/p-RIPK3 Pathway
阿戈美拉汀通过TNF-α/NF-κB/p-RIPK3通路抑制炎症和坏死性凋亡，从而减轻肥胖胰岛素抵抗大鼠的肾损伤
期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26051940
Promsan, Sasivimon; Pengrattanachot, Nattavadee; Phengpol, Nichakorn; Sutthasupha, Prempree; Thongnak, La-Ongdao; Jaikumkao, Krit; Lungkaphin, Anusorn
信号转导
炎症/感染
Rat
Immunology/Inflammation
毒理研究
代谢
肥胖
免疫/内分泌
TNF-α
表观遗传
凋亡
RIPK3
肾损伤
RIP
炎症
