日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multicentre preclinical profiling of apramycin for the treatment of nontuberculous mycobacteria

阿普拉霉素治疗非结核分枝杆菌的多中心临床前研究

Nguyen, Minh-Vu H; Plattner, Michel; Verma, Deepshikha; Krishnamurthy, Ramya V; Xie, Min; Calado Nogueira de Moura, Vinicius; Haldimann, Klara; Lang, Ramon; Becker, Katja; Kaur, Parvinder; Shandil, Radha Krishan; Singh, Mayas; Bulman, Zackery P; Dick, Thomas; Narayanan, Shridhar; Schulthess, Bettina; Mitarai, Satoshi; Daley, Charles L; Hobbie, Sven N

G1405 Ribosomal Methyltransferase-Driven Antibacterial Resistance Affects the 4,5-Disubstituted-2-deoxystreptamine Class of Aminoglycoside Antibiotics

G1405 核糖体甲基转移酶驱动的抗菌耐药性影响 4,5-二取代-2-脱氧链霉胺类氨基糖苷类抗生素

Hobbie, Sven N; Vasella, Andrea; Böttger, Erik C; Crich, David

Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus

前药氟苯尼考胺通过固有耐药性激活,靶向脓肿分枝杆菌。

Phelps, Gregory A; Kurt, Sinem; Jenner, Alexander R; Anderson, Shelby M; Jayasinghe, Thalina D; Griffith, Elizabeth C; Thompson, Carl W; Yang, Lei; Wicki, Basil; Bright, Frederick K; Loudon, Victoria; Wright, William C; Srivastava, Ashish; Singh, Amarinder; Thalluri, Bhargavi; Park, Hyunseo; Lee, Robin B; Wright, Anna K; Grant-Chapman, Oliver; Conner, Daryl K; Troyer, Brennen T; Iverson, Amy; Ochoado, Jason; Pagala, Vishwajeeth R; Wu, Long; Byrum, Stephanie; Fu, Yingxue; Yuan, Zu-Fei; High, Anthony A; Schulthess, Bettina; Rosch, Jason W; Geeleher, Paul; Hobbie, Sven N; Boeck, Lucas; Meibohm, Bernd; Obregon-Henao, Andres; Sander, Peter; Lee, Richard E

Synthesis of Methyl Aprabiosaminide and 2-Hydroxyapramycin from Apramycin

由阿普拉霉素合成甲基阿普拉比索胺和2-羟基阿普拉霉素

Kasdekar, Niteshlal; Spieker, Michael R; Vasella, Andrea; Hobbie, Sven N; Crich, David

Model-informed drug development for antimicrobials: translational pharmacokinetic-pharmacodynamic modelling of apramycin to facilitate prediction of efficacious dose in complicated urinary tract infections

基于模型指导的抗菌药物研发:阿普拉霉素转化药代动力学-药效学模型在预测复杂尿路感染有效剂量中的应用

Hernández-Lozano, Irene; Aranzana-Climent, Vincent; Cao, Sha; Matias, Carina; Ulf Hansen, Jon; Liepinsh, Edgars; Hughes, Diarmaid; Hobbie, Sven N; Vingsbo Lundberg, Carina; Friberg, Lena E

Correction: Synthesis and antibacterial action of 3',6'-disubstituted spectinomycins

更正:3',6'-二取代壮观霉素的合成及其抗菌作用

Dharuman, Suresh; Phelps, Gregory A; Dunn, Christine M; Wilt, Laura A; Murphy, Patricia A; Lee, Robin B; Snoke, Hannah E; Selchow, Petra; Haldimann, Klara; Böttger, Erik C; Hobbie, Sven N; Sander, Peter; Lee, Richard E

Evaluation of the Allplex NG & DR assay for molecular prediction of ciprofloxacin and azithromycin resistance in Neisseria gonorrhoeae

评估 Allplex NG & DR 检测方法在淋病奈瑟菌环丙沙星和阿奇霉素耐药性分子预测中的应用

Roditscheff, Anna; Egli, Konrad; Vianin, Andréj; Lörtscher, Fabian; Reidla, Jürgen; Wehrli, Faina; Risch, Martin; Risch, Lorenz; Hobbie, Sven N; Wohlwend, Nadia; Bodmer, Thomas

Phenotypic Differentiation Within the aac(6') Aminoglycoside Resistance Gene Family Suggests a Novel Subtype IV of Contemporary Clinical Relevance

aac(6')氨基糖苷类耐药基因家族的表型分化提示了一种具有当代临床意义的新型IV亚型

Plattner, Michel; Catelani, Maurizio; Gmür, Sarah-Lisa; Hartmann, Maximilian; Kiliç, Fatmanur; Haldimann, Klara; Crich, David; Hobbie, Sven N

L-carnitine co-administration prevents colistin-induced mitochondrial permeability transition and reduces the risk of acute kidney injury in mice

左旋肉碱联合给药可预防粘菌素诱导的线粒体通透性转变并降低小鼠急性肾损伤的风险

Sophia L Samodelov, Zhibo Gai, Francesca De Luca, Klara Haldimann, Sven N Hobbie, Daniel Müller, Gerd A Kullak-Ublick, Michele Visentin

In vitro susceptibility of Neisseria gonorrhoeae to netilmicin and etimicin in comparison to gentamicin and other aminoglycosides

体外试验中淋病奈瑟菌对奈替米星和依替米星的敏感性与庆大霉素和其他氨基糖苷类抗生素的敏感性比较

Gross, Sonja; Herren, Sebastian; Gysin, Marina; Rominski, Anna; Roditscheff, Anna; Risch, Martin; Imkamp, Frank; Crich, David; Hobbie, Sven N