日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hsp70 Negatively Regulates Autophagy via Governing AMPK Activation, and Dual Hsp70-Autophagy Inhibition Induces Synergetic Cell Death in NSCLC Cells

Hsp70 通过调控 AMPK 激活来负向调控自噬,双重 Hsp70-自噬抑制可诱导 NSCLC 细胞发生协同细胞死亡

Bashar Alhasan, Yana A Gladova, Dmitry V Sverchinsky, Nikolai D Aksenov, Boris A Margulis, Irina V Guzhova

Autocrine regulation of tumor cell repopulation by Hsp70-HMGB1 alarmin complex

Hsp70-HMGB1 报警素复合物对肿瘤细胞再增殖的自分泌调节

Dmitry V Sverchinsky #, Bashar A Alhasan #, Marina A Mikeladze #, Vladimir F Lazarev, Liubov S Kuznetcova, Alisa V Morshneva, Alina D Nikotina, Amr Ziewanah, Lidia V Koludarova, Tatiana Y Starkova, Boris A Margulis, Irina V Guzhova

The molecular chaperone Hsp70 from the thermotolerant Diptera species differs from the Drosophila paralog in its thermostability and higher refolding capacity at extreme temperatures

来自耐热双翅目昆虫的分子伴侣Hsp70与果蝇的旁系同源物相比,其热稳定性更高,且在极端温度下具有更强的重折叠能力。

Garbuz, David G; Sverchinsky, Dmitry; Davletshin, Artem; Margulis, Boris A; Mitkevich, Vladimir; Kulikov, Aleksei M; Evgen'ev, Michael B

Sensitizing tumor cells to conventional drugs: HSP70 chaperone inhibitors, their selection and application in cancer models

提高肿瘤细胞对传统药物的敏感性:HSP70分子伴侣抑制剂及其在癌症模型中的选择和应用

Lazarev, Vladimir F; Sverchinsky, Dmitry V; Mikhaylova, Elena R; Semenyuk, Pavel I; Komarova, Elena Y; Niskanen, Sergey A; Nikotina, Alina D; Burakov, Anton V; Kartsev, Viktor G; Guzhova, Irina V; Margulis, Boris A