日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cytotoxic CD4 development requires CD4 effectors to concurrently recognize local antigen and encounter type I IFN-induced IL-15

细胞毒性 CD4 的发育需要 CD4 效应细胞同时识别局部抗原并遇到 I 型干扰素诱导的 IL-15。

Devarajan, Priyadharshini; Vong, Allen M; Castonguay, Catherine H; Silverstein, Noah J; Kugler-Umana, Olivia; Bautista, Bianca L; Kelly, Karen A; Luban, Jeremy; Swain, Susan L

CD4 memory has a hierarchical structure created by requirements for infection-derived signals at an effector checkpoint

CD4记忆具有层级结构,这是由效应检查点对感染衍生信号的需求所决定的。

Swain, Susan L

Strong influenza-induced T(FH) generation requires CD4 effectors to recognize antigen locally and receive signals from continuing infection

流感病毒诱导的T(FH)细胞生成需要CD4效应细胞在局部识别抗原并接收来自持续感染的信号。

Devarajan, Priyadharshini; Vong, Allen M; Castonguay, Catherine H; Kugler-Umana, Olivia; Bautista, Bianca L; Jones, Michael C; Kelly, Karen A; Xia, Jingya; Swain, Susan L

IgD(+) age-associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged

IgD(+) 年龄相关 B 细胞是主要的 T 细胞非依赖性 B 细胞应答的祖细胞,该应答可产生保护性抗体,并且可通过灭活疫苗在老年人群中诱导产生。

Kugler-Umana, Olivia; Zhang, Wenliang; Kuang, Yi; Liang, Jialing; Castonguay, Catherine H; Tonkonogy, Susan L; Marshak-Rothstein, Ann; Devarajan, Priyadharshini; Swain, Susan L

Bona Fide Th17 Cells without Th1 Functional Plasticity Protect against Influenza

不具备 Th1 功能可塑性的真正 Th17 细胞可抵抗流感

Dhume, Kunal; Finn, Caroline M; Devarajan, Priyadharshini; Singh, Ayushi; Tejero, Joanne D; Prokop, Emily; Strutt, Tara M; Sell, Stewart; Swain, Susan L; McKinstry, Karl Kai

CD25-Targeted IL-2 Signals Promote Improved Outcomes of Influenza Infection and Boost Memory CD4 T Cell Formation

CD25靶向IL-2信号促进流感感染预后改善并增强记忆性CD4 T细胞形成

Alam, Fahmida; Singh, Ayushi; Flores-Malavet, Valeria; Sell, Stewart; Cooper, Andrea M; Swain, Susan L; McKinstry, K Kai; Strutt, Tara M

Understanding the Heterogeneous Population of Age-Associated B Cells and Their Contributions to Autoimmunity and Immune Response to Pathogens

了解与年龄相关的B细胞异质性群体及其对自身免疫和病原体免疫反应的贡献

Kugler-Umana, Olivia; Devarajan, Priyadharshini; Swain, Susan L

Original Antigenic Sin: Friend or Foe in Developing a Broadly Cross-Reactive Vaccine to Influenza?

原抗原罪:在研发广谱交叉反应流感疫苗中是朋友还是敌人?

Devarajan, Priyadharshini; Swain, Susan L

Memory CD4 T cell-derived IL-2 synergizes with viral infection to exacerbate lung inflammation

记忆性CD4 T细胞衍生的IL-2与病毒感染协同作用,加剧肺部炎症。

McKinstry, K Kai; Alam, Fahmida; Flores-Malavet, Valeria; Nagy, Mate Z; Sell, Stewart; Cooper, Andrea M; Swain, Susan L; Strutt, Tara M

Pathogen Recognition by CD4 Effectors Drives Key Effector and Most Memory Cell Generation Against Respiratory Virus

CD4效应细胞对病原体的识别驱动关键效应细胞和大多数记忆细胞的生成,从而对抗呼吸道病毒

Devarajan, Priyadharshini; Jones, Michael C; Kugler-Umana, Olivia; Vong, Allen M; Xia, Jingya; Swain, Susan L