日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

XBP1s-EDEM2 Prevents the Onset and Development of HFpEF by Ameliorating Cardiac Lipotoxicity

XBP1s-EDEM2通过改善心脏脂毒性来预防HFpEF的发生和发展

Fonseka, Oveena; Raja, Rida; Ross, Claire; Gare, Sanskruti R; Zhang, Jiayan; Hille, Susanne S; King, Katharine; Ruiz-Velasco, Andrea; Kaur, Namrita; Chen, Xinyi; Miller, Jessica M; Abouleisa, Riham R E; Ou, Qinghui; Zou, Zhiyong; Zhao, Xiangjun; Sotomayor-Flores, Cristian; Frank, Derk; Swanton, Eileithyia; Pool, Martin R; Missaglia, Sara; Tavian, Daniela; Schiattarella, Gabriele G; Wang, Tao; Venetucci, Luigi; Pinali, Christian; Rutter, Martin K; Keavney, Bernard D; Cartwright, Elizabeth J; Mohamed, Tamer M A; Müller, Oliver J; Liu, Wei

Dual Action of Eeyarestatin 24 on Sec-Dependent Protein Secretion and Bacterial DNA

Eeyarestatin 24 对 Sec 依赖性蛋白分泌和细菌 DNA 的双重作用

Schäfer, Ann-Britt; Steenhuis, Maurice; Jim, Kin Ki; Neef, Jolanda; O'Keefe, Sarah; Whitehead, Roger C; Swanton, Eileithyia; Wang, Biwen; Halbedel, Sven; High, Stephen; van Dijl, Jan Maarten; Luirink, Joen; Wenzel, Michaela

Eeyarestatin 24 impairs SecYEG-dependent protein trafficking and inhibits growth of clinically relevant pathogens

Eeyarestatin 24 会损害 SecYEG 依赖性蛋白质运输并抑制临床相关病原体的生长。

Steenhuis, Maurice; Koningstein, Gregory M; Oswald, Julia; Pick, Tillman; O'Keefe, Sarah; Koch, Hans-Georg; Cavalié, Adolfo; Whitehead, Roger C; Swanton, Eileithyia; High, Stephen; Luirink, Joen

Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response

Pak2作为心脏保护性内质网应激反应的新型治疗靶点

Binder, Pablo; Wang, Shunyao; Radu, Maria; Zin, Min; Collins, Lucy; Khan, Saba; Li, Yatong; Sekeres, Karolina; Humphreys, Neil; Swanton, Eileithyia; Reid, Adam; Pu, Fay; Oceandy, Delvac; Guan, Kaomei; Hille, Susanne S; Frey, Norbert; Müller, Oliver J; Cartwright, Elizabeth J; Chernoff, Jonathan; Wang, Xin; Liu, Wei

Increased intracellular proteolysis reduces disease severity in an ER stress-associated dwarfism

细胞内蛋白水解增加可减轻内质网应激相关侏儒症的疾病严重程度。

Mullan, Lorna A; Mularczyk, Ewa J; Kung, Louise H; Forouhan, Mitra; Wragg, Jordan Ma; Goodacre, Royston; Bateman, John F; Swanton, Eileithyia; Briggs, Michael D; Boot-Handford, Raymond P

Transmembrane domain quality control systems operate at the endoplasmic reticulum and Golgi apparatus

跨膜结构域质量控制系统在内质网和高尔基体中发挥作用。

Briant, Kit; Johnson, Nicholas; Swanton, Eileithyia

The Plasma Membrane Calcium Pump in Pancreatic Cancer Cells Exhibiting the Warburg Effect Relies on Glycolytic ATP.

胰腺癌细胞中表现出瓦博格效应的质膜钙泵依赖于糖酵解ATP

James Andrew D, Patel Waseema, Butt Zohra, Adiamah Magretta, Dakhel Raga, Latif Ayse, Uggenti Carolina, Swanton Eileithyia, Imamura Hiromi, Siriwardena Ajith K, Bruce Jason I E

ERAD of proteins containing aberrant transmembrane domains requires ubiquitylation of cytoplasmic lysine residues

含有异常跨膜结构域的蛋白质的内质网相关降解(ERAD)需要胞质赖氨酸残基的泛素化。

Briant, Kit; Koay, Yee-Hui; Otsuka, Yuka; Swanton, Eileithyia

Inhibition of protein translocation at the endoplasmic reticulum promotes activation of the unfolded protein response

抑制内质网蛋白质转位可促进未折叠蛋白反应的激活。

McKibbin, Craig; Mares, Alina; Piacenti, Michela; Williams, Helen; Roboti, Peristera; Puumalainen, Marjo; Callan, Anna C; Lesiak-Mieczkowska, Karolina; Linder, Stig; Harant, Hanna; High, Stephen; Flitsch, Sabine L; Whitehead, Roger C; Swanton, Eileithyia

Differences in endoplasmic-reticulum quality control determine the cellular response to disease-associated mutants of proteolipid protein

内质网质量控制的差异决定了细胞对与疾病相关的蛋白脂质蛋白突变体的反应。

Roboti, Peristera; Swanton, Eileithyia; High, Stephen