日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Plasma Aβ(42)/Aβ(40) is sensitive to early cerebral amyloid accumulation and predicts risk of cognitive decline across the Alzheimer's disease spectrum

血浆Aβ(42)/Aβ(40)比值对早期脑淀粉样蛋白沉积敏感,并可预测阿尔茨海默病谱系中认知功能下降的风险。

Trelle, Alexandra N; Young, Christina B; Vossler, Hillary; Ramos Benitez, Javier; Cody, Karly A; Mendiola, Justin H; Swarovski, Michelle S; Guen, Yann Le; Feinstein, Igor; Butler, Robert R 3rd; Channappa, Divya; Romero, America; Park, Jennifer; Shahid-Besanti, Marian; Corso, Nicole K; Chau, Kelly; Smith, Amanda N; Skylar-Scott, Irina; Yutsis, Maya V; Fredericks, Carolyn A; Tian, Lu; Younes, Kyan; Kerchner, Geoffrey A; Deutsch, Gayle K; Davidzon, Guido A; Sha, Sharon J; Henderson, Victor W; Longo, Frank M; Greicius, Michael D; Wyss-Coray, Tony; Andreasson, Katrin I; Poston, Kathleen L; Wagner, Anthony D; Mormino, Elizabeth C; Wilson, Edward N

Parkinson's disease is characterized by vitamin B6-dependent inflammatory kynurenine pathway dysfunction.

帕金森病的特征是维生素 B6 依赖性炎症犬尿氨酸通路功能障碍

Wilson Edward N, Umans Jacob, Swarovski Michelle S, Minhas Paras S, Mendiola Justin H, Midttun Øivind, Ulvik Arve, Shahid-Besanti Marian, Linortner Patricia, Mhatre Siddhita D, Wang Qian, Channappa Divya, Corso Nicole K, Tian Lu, Fredericks Carolyn A, Kerchner Geoffrey A, Plowey Edward D, Cholerton Brenna, Ueland Per M, Zabetian Cyrus P, Gray Nora E, Quinn Joseph F, Montine Thomas J, Sha Sharon J, Longo Frank M, Wolk David A, Chen-Plotkin Alice, Henderson Victor W, Wyss-Coray Tony, Wagner Anthony D, Mormino Elizabeth C, Aghaeepour Nima, Poston Kathleen L, Andreasson Katrin I

TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models

TREM1 会破坏衰老和阿尔茨海默病小鼠模型中的髓系生物能量学和认知功能。

Edward N Wilson ,Congcong Wang ,Michelle S Swarovski ,Kristy A Zera ,Hannah E Ennerfelt ,Qian Wang ,Aisling Chaney ,Esha Gauba ,Javier A Ramos Benitez ,Yann Le Guen ,Paras S Minhas ,Maharshi Panchal ,Yuting J Tan ,Eran Blacher ,Chinyere A Iweka ,Haley Cropper ,Poorva Jain ,Qingkun Liu ,Swapnil S Mehta ,Abigail J Zuckerman ,Matthew Xin ,Jacob Umans ,Jolie Huang ,Aarooran S Durairaj ,Geidy E Serrano ,Thomas G Beach ,Michael D Greicius ,Michelle L James ,Marion S Buckwalter ,Melanie R McReynolds ,Joshua D Rabinowitz ,Katrin I Andreasson

Parkinson's disease is characterized by vitamin B6-dependent inflammatory kynurenine pathway dysfunction

帕金森病以维生素B6依赖性炎症性犬尿氨酸通路功能障碍为特征。

Wilson, Edward; Umans, Jacob; Swarovski, Michelle; Minhas, Paras; Midttun, Øivind; Ulvik, Arve Arve; Shahid-Besanti, Marian; Linortner, Patricia; Mhatre, Siddhita; Wang, Qian; Channappa, Divya; Corso, Nicole; Tian, Lu; Fredericks, Carolyn; Kerchner, Geoffrey; Plowey, Edward; Cholerton, Brenna; Ueland, Per; Zabetian, Cyrus; Gray, Nora; Quinn, Joseph; Montine, Thomas; Sha, Sharon; Longo, Frank; Wolk, David; Chen-Plotkin, Alice; Henderson, Victor; Wyss-Coray, Tony; Wagner, Anthony; Mormino, Elizabeth; Aghaeepour, Nima; Poston, Kathleen; Andreasson, Katrin

Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer's disease

全自动Lumipulse血浆磷酸化tau181检测在阿尔茨海默病诊断中的性能

Wilson, Edward N; Young, Christina B; Ramos Benitez, Javier; Swarovski, Michelle S; Feinstein, Igor; Vandijck, Manu; Le Guen, Yann; Kasireddy, Nandita M; Shahid, Marian; Corso, Nicole K; Wang, Qian; Kennedy, Gabriel; Trelle, Alexandra N; Lind, Betty; Channappa, Divya; Belnap, Malia; Ramirez, Veronica; Skylar-Scott, Irina; Younes, Kyan; Yutsis, Maya V; Le Bastard, Nathalie; Quinn, Joseph F; van Dyck, Christopher H; Nairn, Angus; Fredericks, Carolyn A; Tian, Lu; Kerchner, Geoffrey A; Montine, Thomas J; Sha, Sharon J; Davidzon, Guido; Henderson, Victor W; Longo, Frank M; Greicius, Michael D; Wagner, Anthony D; Wyss-Coray, Tony; Poston, Kathleen L; Mormino, Elizabeth C; Andreasson, Katrin I

Plasma Biomarkers of Tau and Neurodegeneration During Major Cardiac and Noncardiac Surgery

心脏和非心脏大手术期间血浆中Tau蛋白和神经退行性变生物标志物的变化

Feinstein, Igor; Wilson, Edward N; Swarovski, Michelle S; Andreasson, Katrin I; Angst, Martin S; Greicius, Michael D

Association of CSF Biomarkers With Hippocampal-Dependent Memory in Preclinical Alzheimer Disease

脑脊液生物标志物与临床前阿尔茨海默病海马依赖性记忆的关联

Trelle, Alexandra N; Carr, Valerie A; Wilson, Edward N; Swarovski, Michelle S; Hunt, Madison P; Toueg, Tyler N; Tran, Tammy T; Channappa, Divya; Corso, Nicole K; Thieu, Monica K; Jayakumar, Manasi; Nadiadwala, Ayesha; Guo, Wanjia; Tanner, Natalie J; Bernstein, Jeffrey D; Litovsky, Celia P; Guerin, Scott A; Khazenzon, Anna M; Harrison, Marc B; Rutt, Brian K; Deutsch, Gayle K; Chin, Frederick T; Davidzon, Guido A; Hall, Jacob N; Sha, Sharon J; Fredericks, Carolyn A; Andreasson, Katrin I; Kerchner, Geoffrey A; Wagner, Anthony D; Mormino, Elizabeth C

Soluble TREM2 is elevated in Parkinson's disease subgroups with increased CSF tau

在脑脊液 tau 水平升高的帕金森病亚组中,可溶性 TREM2 水平升高

Edward N Wilson, Michelle S Swarovski, Patricia Linortner, Marian Shahid, Abigail J Zuckerman, Qian Wang, Divya Channappa, Paras S Minhas, Siddhita D Mhatre, Edward D Plowey, Joseph F Quinn, Cyrus P Zabetian, Lu Tian, Frank M Longo, Brenna Cholerton, Thomas J Montine, Kathleen L Poston, Katrin I And

Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity

外周 TREM1 对大脑和肠道免疫原的反应会加剧中风的严重程度

Qingkun Liu, Emily M Johnson, Rachel K Lam, Qian Wang, Hong Bo Ye, Edward N Wilson, Paras S Minhas, Ling Liu, Michelle S Swarovski, Stephanie Tran, Jing Wang, Swapnil S Mehta, Xi Yang, Joshua D Rabinowitz, Samuel S Yang, Mehrdad Shamloo, Christoph Mueller, Michelle L James, Katrin I Andreasson1