日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CD4+ and CD8+ T cells are required to prevent SARS-CoV-2 persistence in the nasal compartment

CD4+ 和 CD8+ T 细胞是防止 SARS-CoV-2 在鼻腔中持续存在所必需的

Meenakshi Kar, Katherine E E Johnson, Abigail Vanderheiden, Elizabeth J Elrod, Katharine Floyd, Elizabeth Geerling, E Taylor Stone, Eduardo Salinas, Stephanie Banakis, Wei Wang, Shruti Sathish, Swathi Shrihari, Meredith E Davis-Gardner, Jacob Kohlmeier, Amelia Pinto, Robyn Klein, Arash Grakoui, Elod

A broadly reactive antibody targeting the N-terminal domain of SARS-CoV-2 spike confers Fc-mediated protection

针对 SARS-CoV-2 刺突的 N 端结构域的广谱抗体可提供 Fc 介导的保护作用

Lucas J Adams, Laura A VanBlargan, Zhuoming Liu, Pavlo Gilchuk, Haiyan Zhao, Rita E Chen, Saravanan Raju, Zhenlu Chong, Bradley M Whitener, Swathi Shrihari, Prashant N Jethva, Michael L Gross, James E Crowe Jr, Sean P J Whelan, Michael S Diamond, Daved H Fremont

Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein

识别 SARS-CoV-2 刺突蛋白 N 端结构域的中和和保护性人单克隆抗体

Naveenchandra Suryadevara, Swathi Shrihari, Pavlo Gilchuk, Laura A VanBlargan, Elad Binshtein, Seth J Zost, Rachel S Nargi, Rachel E Sutton, Emma S Winkler, Elaine C Chen, Mallorie E Fouch, Edgar Davidson, Benjamin J Doranz, Rita E Chen, Pei-Yong Shi, Robert H Carnahan, Larissa B Thackray, Michael S

Ultrapotent miniproteins targeting the SARS-CoV-2 receptor-binding domain protect against infection and disease

针对 SARS-CoV-2 受体结合域的超强微蛋白可预防感染和疾病

James Brett Case, Rita E Chen, Longxing Cao, Baoling Ying, Emma S Winkler, Max Johnson, Inna Goreshnik, Minh N Pham, Swathi Shrihari, Natasha M Kafai, Adam L Bailey, Xuping Xie, Pei-Yong Shi, Rashmi Ravichandran, Lauren Carter, Lance Stewart, David Baker, Michael S Diamond

An intranasal vaccine durably protects against SARS-CoV-2 variants in mice

鼻内疫苗可持久保护小鼠免受SARS-CoV-2变种病毒感染。

Ahmed O Hassan ,Swathi Shrihari ,Matthew J Gorman ,Baoling Ying ,Dansu Yuan ,Saravanan Raju ,Rita E Chen ,Igor P Dmitriev ,Elena Kashentseva ,Lucas J Adams ,Colin Mann ,Meredith E Davis-Gardner ,Mehul S Suthar ,Pei-Yong Shi ,Erica Ollmann Saphire ,Daved H Fremont ,David T Curiel ,Galit Alter ,Michael S Diamond

Ultrapotent miniproteins targeting the receptor-binding domain protect against SARS-CoV-2 infection and disease in mice

针对受体结合域的超强效微蛋白可保护小鼠免受 SARS-CoV-2 感染和疾病

James Brett Case, Rita E Chen, Longxing Cao, Baoling Ying, Emma S Winkler, Inna Goreshnik, Swathi Shrihari, Natasha M Kafai, Adam L Bailey, Xuping Xie, Pei-Yong Shi, Rashmi Ravichandran, Lauren Carter, Lance Stewart, David Baker, Michael S Diamond0

Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

快速分离和分析多种靶向SARS-CoV-2刺突蛋白的人源单克隆抗体

Seth J Zost # ,Pavlo Gilchuk # ,Rita E Chen ,James Brett Case ,Joseph X Reidy ,Andrew Trivette ,Rachel S Nargi ,Rachel E Sutton ,Naveenchandra Suryadevara ,Elaine C Chen ,Elad Binshtein ,Swathi Shrihari ,Mario Ostrowski ,Helen Y Chu ,Jonathan E Didier ,Keith W MacRenaris ,Taylor Jones ,Samuel Day ,Luke Myers ,F Eun-Hyung Lee ,Doan C Nguyen ,Ignacio Sanz ,David R Martinez ,Paul W Rothlauf ,Louis-Marie Bloyet ,Sean P J Whelan ,Ralph S Baric ,Larissa B Thackray ,Michael S Diamond ,Robert H Carnahan ,James E Crowe Jr

A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies

小鼠 SARS-CoV-2 感染模型显示中和抗体具有保护作用

Ahmed O Hassan, James Brett Case, Emma S Winkler, Larissa B Thackray, Natasha M Kafai, Adam L Bailey, Broc T McCune, Julie M Fox, Rita E Chen, Wafaa B Alsoussi, Jackson S Turner, Aaron J Schmitz, Tingting Lei, Swathi Shrihari, Shamus P Keeler, Daved H Fremont, Suellen Greco, Paul B McCray Jr, Stanle

A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2

单剂量鼻内接种ChAd疫苗可保护上下呼吸道免受SARS-CoV-2病毒感染。

Ahmed O Hassan ,Natasha M Kafai ,Igor P Dmitriev ,Julie M Fox ,Brittany K Smith ,Ian B Harvey ,Rita E Chen ,Emma S Winkler ,Alex W Wessel ,James Brett Case ,Elena Kashentseva ,Broc T McCune ,Adam L Bailey ,Haiyan Zhao ,Laura A VanBlargan ,Ya-Nan Dai ,Meisheng Ma ,Lucas J Adams ,Swathi Shrihari ,Jonathan E Danis ,Lisa E Gralinski ,Yixuan J Hou ,Alexandra Schäfer ,Arthur S Kim ,Shamus P Keeler ,Daniela Weiskopf ,Ralph S Baric ,Michael J Holtzman ,Daved H Fremont ,David T Curiel ,Michael S Diamond

The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis

肠道微生物组通过胆汁酸-I 型干扰素信号轴限制甲病毒的感染和传播

Emma S Winkler, Swathi Shrihari, Barry L Hykes Jr, Scott A Handley, Prabhakar S Andhey, Yan-Jang S Huang, Amanda Swain, Lindsay Droit, Kranthi K Chebrolu, Matthias Mack, Dana L Vanlandingham, Larissa B Thackray, Marina Cella, Marco Colonna, Maxim N Artyomov, Thaddeus S Stappenbeck, Michael S Diamond