日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Editor's Highlight: High-Throughput Functional Genomics Identifies Modulators of TCE Metabolite Genotoxicity and Candidate Susceptibility Genes

编辑推荐:高通量功能基因组学鉴定出三氯乙烯代谢物遗传毒性的调节因子和候选易感基因

De La Rosa, Vanessa Y; Asfaha, Jonathan; Fasullo, Michael; Loguinov, Alex; Li, Peng; Moore, Lee E; Rothman, Nathaniel; Nakamura, Jun; Swenberg, James A; Scelo, Ghislaine; Zhang, Luoping; Smith, Martyn T; Vulpe, Chris D

DNA Product Formation in Female Sprague-Dawley Rats Following Polyhalogenated Aromatic Hydrocarbon (PHAH) Exposure

多卤代芳烃(PHAH)暴露后雌性Sprague-Dawley大鼠DNA产物的形成

Gao, Lina; Mutlu, Esra; Collins, Leonard B; Walker, Nigel J; Hartwell, Hadley J; Olson, James R; Sun, Wei; Gold, Avram; Ball, Louise M; Swenberg, James A

N(6)-Formyllysine as a Biomarker of Formaldehyde Exposure: Formation and Loss of N(6)-Formyllysine in Nasal Epithelium in Long-Term, Low-Dose Inhalation Studies in Rats

N(6)-甲酰赖氨酸作为甲醛暴露的生物标志物:大鼠长期低剂量吸入研究中鼻上皮细胞中N(6)-甲酰赖氨酸的形成和丢失

Edrissi, Bahar; Taghizadeh, Koli; Moeller, Benjamin C; Yu, Rui; Kracko, Dean; Doyle-Eisele, Melanie; Swenberg, James A; Dedon, Peter C

Measurement of Endogenous versus Exogenous Formaldehyde-Induced DNA-Protein Crosslinks in Animal Tissues by Stable Isotope Labeling and Ultrasensitive Mass Spectrometry

利用稳定同位素标记和超灵敏质谱法测定动物组织中内源性和外源性甲醛诱导的DNA-蛋白质交联

Lai, Yongquan; Yu, Rui; Hartwell, Hadley J; Moeller, Benjamin C; Bodnar, Wanda M; Swenberg, James A

Polychlorinated Biphenyls Induce Oxidative DNA Adducts in Female Sprague-Dawley Rats

多氯联苯诱导雌性Sprague-Dawley大鼠DNA氧化加合物形成

Mutlu, Esra; Gao, Lina; Collins, Leonard B; Walker, Nigel J; Hartwell, Hadley J; Olson, James R; Sun, Wei; Gold, Avram; Ball, Louise M; Swenberg, James A

Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations

低水平的氧化应激可诱导DNA损伤簇,进而导致NHEJ介导的突变。

Sharma, Vyom; Collins, Leonard B; Chen, Ting-Huei; Herr, Natalie; Takeda, Shunichi; Sun, Wei; Swenberg, James A; Nakamura, Jun

Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung

15q15.2染色体位点在调控UBR1和使吸烟者易患肺组织MGMT甲基化中的作用

Leng, Shuguang; Wu, Guodong; Collins, Leonard B; Thomas, Cynthia L; Tellez, Carmen S; Jauregui, Andrew R; Picchi, Maria A; Zhang, Xiequn; Juri, Daniel E; Desai, Dhimant; Amin, Shantu G; Crowell, Richard E; Stidley, Christine A; Liu, Yushi; Swenberg, James A; Lin, Yong; Wathelet, Marc G; Gilliland, Frank D; Belinsky, Steven A

Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen

内源性甲醛是一种造血干细胞基因毒素和代谢致癌物

Pontel, Lucas B; Rosado, Ivan V; Burgos-Barragan, Guillermo; Garaycoechea, Juan I; Yu, Rui; Arends, Mark J; Chandrasekaran, Gayathri; Broecker, Verena; Wei, Wei; Liu, Limin; Swenberg, James A; Crossan, Gerry P; Patel, Ketan J

Formation, Accumulation, and Hydrolysis of Endogenous and Exogenous Formaldehyde-Induced DNA Damage

内源性和外源性甲醛诱导的DNA损伤的形成、积累和水解

Yu, Rui; Lai, Yongquan; Hartwell, Hadley J; Moeller, Benjamin C; Doyle-Eisele, Melanie; Kracko, Dean; Bodnar, Wanda M; Starr, Thomas B; Swenberg, James A

Arsenic exposure perturbs the gut microbiome and its metabolic profile in mice: an integrated metagenomics and metabolomics analysis

砷暴露扰乱小鼠肠道微生物群及其代谢谱:一项整合宏基因组学和代谢组学分析

Lu, Kun; Abo, Ryan Phillip; Schlieper, Katherine Ann; Graffam, Michelle E; Levine, Stuart; Wishnok, John S; Swenberg, James A; Tannenbaum, Steven R; Fox, James G