日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia

TCF7-SPI1 与 NRAS(G12D)之间的致癌合作需要 β-catenin 活性来驱动 T 细胞急性淋巴细胞白血病

Quentin Van Thillo #, Jolien De Bie #, Janith A Seneviratne, Sofie Demeyer, Sofia Omari, Anushree Balachandran, Vicki Zhai, Wai L Tam, Bram Sweron, Ellen Geerdens, Olga Gielen, Sarah Provost, Heidi Segers, Nancy Boeckx, Glenn M Marshall, Belamy B Cheung, Kiyotaka Isobe, Itaru Kato, Junko Takita, Tim

T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development

T细胞急性淋巴细胞白血病表达一种独特的截短型FAT1亚型,该亚型与NOTCH1协同作用,参与白血病的发生发展。

de Bock, Charles E; Down, Michelle; Baidya, Kinsha; Sweron, Bram; Boyd, Andrew W; Fiers, Mark; Burns, Gordon F; Molloy, Timothy J; Lock, Richard B; Soulier, Jean; Taghon, Tom; Van Vlierberghe, Pieter; Cools, Jan; Holst, Jeff; Thorne, Rick F

HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development

HOXA9 与激活的 JAK/STAT 信号传导协同作用,促进白血病发展

Charles E de Bock, Sofie Demeyer, Sandrine Degryse, Delphine Verbeke, Bram Sweron, Olga Gielen, Roel Vandepoel, Carmen Vicente, Marlies Vanden Bempt, Antonis Dagklis, Ellen Geerdens, Simon Bornschein, Rik Gijsbers, Jean Soulier, Jules P Meijerink, Merja Heinäniemi, Susanna Teppo, Maria Bouvy-Liivran

The N676D and G697R mutations in the kinase domain of FLT3 confer resistance to the inhibitor AC220

FLT3激酶结构域中的N676D和G697R突变赋予其对抑制剂AC220的耐药性。

Pauwels, Daphnie; Sweron, Bram; Cools, Jan