SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue
SIVcol Nef 通过促进 SERINC5 的蛋白酶体降解来拮抗 SERINC5,但不能有效增强 HIV-1 在人 CD4+ T 细胞和淋巴组织中的复制。
期刊:PLoS Pathogens
影响因子:5.5
doi:10.1371/journal.ppat.1007269
Dorota Kmiec,Bengisu Akbil,Swetha Ananth,Dominik Hotter,Konstantin M J Sparrer,Christina M Stürzel,Birthe Trautz,Ahidjo Ayouba,Martine Peeters,Zhong Yao,Igor Stagljar,Vânia Passos,Thomas Zillinger,Christine Goffinet,Daniel Sauter,Oliver T Fackler,Frank Kirchhoff