日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Axonal organelle buildup from loss of AP-4 complex function causes exacerbation of amyloid plaque pathology and gliosis in Alzheimer's disease mouse model

由于 AP-4 复合物功能丧失而导致的轴突细胞器积聚导致阿尔茨海默病小鼠模型中的淀粉样斑块病理和神经胶质增生加剧

Alex Orlowski, Joseph Karippaparambil, Jean-Michel Paumier, Shraddha Ghanta, Eduardo Pallares, Jamuna Tandukar, Ruixuan Gao, Swetha Gowrishankar

Synaptic vesicle proteins and ATG9A self-organize in distinct vesicle phases within synapsin condensates

突触囊泡蛋白和 ATG9A 在突触蛋白凝聚物内的不同囊泡相中自组织

Daehun Park, Yumei Wu, Xinbo Wang, Swetha Gowrishankar, Aaron Baublis, Pietro De Camilli

Discovery of a Small-Molecule Modulator of the Autophagy-Lysosome Pathway That Targets Lamin A/C and LAMP1, Induces Autophagic Flux, and Affects Lysosome Positioning in Neurons

发现一种靶向层蛋白 A/C 和 LAMP1、诱导自噬通量并影响神经元中溶酶体定位的自噬-溶酶体通路小分子调节剂

Ryan S Hippman, Amanda M Snead, Zoe A Petros, Melissa A Korkmaz-Vaisys, Sruchi Patel, Daniel Sotelo, Andrew Dobria, Maryna Salkovski, Thu T A Nguyen, Ricardo Linares, Stephanie M Cologna, Swetha Gowrishankar, Leslie N Aldrich

The inositol 5-phosphatase INPP5K participates in the fine control of ER organization

肌醇5-磷酸酶INPP5K参与内质网组织的精细控制

Rui Dong, Ting Zhu, Lorena Benedetti, Swetha Gowrishankar, Huichao Deng, Yiying Cai, Xiangming Wang, Kang Shen, Pietro De Camilli1

Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer's disease amyloid plaques

阿尔茨海默病淀粉样斑块中大量积累缺乏腔内蛋白酶的轴突溶酶体

Swetha Gowrishankar, Peng Yuan, Yumei Wu, Matthew Schrag, Summer Paradise, Jaime Grutzendler, Pietro De Camilli, Shawn M Ferguson