日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Key transcriptional effectors of the pancreatic acinar phenotype and oncogenic transformation

胰腺腺泡表型和癌变转化的关键转录效应因子

Azevedo-Pouly, Ana; Hale, Michael A; Swift, Galvin H; Hoang, Chinh Q; Deering, Tye G; Xue, Jumin; Wilkie, Thomas M; Murtaugh, L Charles; MacDonald, Raymond J

Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A

PTF1A通过转录维持胰腺腺泡的特性、分化和稳态

Hoang, Chinh Q; Hale, Michael A; Azevedo-Pouly, Ana C; Elsässer, Hans P; Deering, Tye G; Willet, Spencer G; Pan, Fong C; Magnuson, Mark A; Wright, Christopher V E; Swift, Galvin H; MacDonald, Raymond J

MIST1 and PTF1 Collaborate in Feed-Forward Regulatory Loops That Maintain the Pancreatic Acinar Phenotype in Adult Mice.

MIST1 和 PTF1 在前馈调控回路中协同作用,维持成年小鼠的胰腺腺泡表型

Jiang Mei, Azevedo-Pouly Ana C, Deering Tye G, Hoang Chinh Q, DiRenzo Daniel, Hess David A, Konieczny Stephen F, Swift Galvin H, MacDonald Raymond J

A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics

一种快速体内筛选胰腺导管腺癌治疗药物的方法

Ocal, Ozhan; Pashkov, Victor; Kollipara, Rahul K; Zolghadri, Yalda; Cruz, Victoria H; Hale, Michael A; Heath, Blake R; Artyukhin, Alex B; Christie, Alana L; Tsoulfas, Pantelis; Lorens, James B; Swift, Galvin H; Brekken, Rolf A; Wilkie, Thomas M

The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis

核激素受体家族成员NR5A2在胰腺器官发生过程中控制多能祖细胞的形成和腺泡分化的某些方面。

Hale, Michael A; Swift, Galvin H; Hoang, Chinh Q; Deering, Tye G; Masui, Toshi; Lee, Youn-Kyoung; Xue, Jumin; MacDonald, Raymond J

Program specificity for Ptf1a in pancreas versus neural tube development correlates with distinct collaborating cofactors and chromatin accessibility

Ptf1a在胰腺发育和神经管发育中的程序特异性与不同的协同辅助因子和染色质可及性相关。

Meredith, David M; Borromeo, Mark D; Deering, Tye G; Casey, Bradford H; Savage, Trisha K; Mayer, Paul R; Hoang, Chinh; Tung, Kuang-Chi; Kumar, Manonmani; Shen, Chengcheng; Swift, Galvin H; Macdonald, Raymond J; Johnson, Jane E

Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells

PTF1复合物中Rbpj被Rbpjl取代,控制着胰腺腺泡细胞的最终成熟。

Masui, Toshihiko; Swift, Galvin H; Deering, Tye; Shen, Chengcheng; Coats, Ward S; Long, Qiaoming; Elsässer, Hans-Peter; Magnuson, Mark A; MacDonald, Raymond J

Transcriptional autoregulation controls pancreatic Ptf1a expression during development and adulthood

转录自调控在发育和成年期控制胰腺 Ptf1a 的表达

Masui, Toshihiko; Swift, Galvin H; Hale, Michael A; Meredith, David M; Johnson, Jane E; Macdonald, Raymond J

PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L

PTF1 是一种器官特异性且不依赖于 Notch 信号通路的碱性螺旋-环-螺旋复合物,其中包含哺乳动物无毛抑制因子 (RBP-J) 或其旁系同源物 RBP-L。

Beres, Thomas M; Masui, Toshihiko; Swift, Galvin H; Shi, Ling; Henke, R Michael; MacDonald, Raymond J

Pancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas development

胰十二指肠同源框1在胰腺发育过程中调控肝脏受体同源物1的表达

Annicotte, Jean-Sébastien; Fayard, Elisabeth; Swift, Galvin H; Selander, Lars; Edlund, Helena; Tanaka, Toshiya; Kodama, Tatsuhiko; Schoonjans, Kristina; Auwerx, Johan