日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
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2025
2026
影响因子:
–

The phosphatase activity of the PPP2R5D-PP2A holoenzyme modulates liprin-α1 liquid-liquid phase separation.

PPP2R5D-PP2A 全酶的磷酸酶活性调节脂蛋白-α1 液-液相分离

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.110349
Mayer Abigail, Derua Rita, Spahn Elijah, Verbinnen Iris, Zhang Yang, Guzman Michelle, Swingle Mark R, Wadzinski Brian E, Honkanen Richard, Janssens Veerle, Xia Houhui
其它
发表日期：2025
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Quantum-based modeling implies that bidentate Arg(89)-substrate binding enhances serine/threonine protein phosphatase-2A(PPP2R5D/PPP2R1A/PPP2CA)-mediated dephosphorylation

基于量子力学的建模表明，双齿Arg(89)底物结合增强了丝氨酸/苏氨酸蛋白磷酸酶-2A(PPP2R5D/PPP2R1A/PPP2CA)介导的去磷酸化作用。

期刊:Frontiers in Cell and Developmental Biology
影响因子:4.3
doi:10.3389/fcell.2023.1141804
Salter, E Alan; Wierzbicki, Andrzej; Honkanen, Richard E; Swingle, Mark R
信号转导
PPP2R5D
磷酸化
发表日期：2023
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Inhibitors of Serine/Threonine Protein Phosphatases: Biochemical and Structural Studies Provide Insight for Further Development

丝氨酸/苏氨酸蛋白磷酸酶抑制剂：生化和结构研究为进一步开发提供见解

期刊:Current Medicinal Chemistry
影响因子:3.5
doi:10.2174/0929867325666180508095242
Swingle, Mark R; Honkanen, Richard E
信号转导
发表日期：2019
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Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C.

PPP家族丝氨酸/苏氨酸蛋白磷酸酶的晶体结构和诱变研究阐明了斑蝥素和新型去甲斑蝥素类PP5C抑制剂的选择性

期刊:Biochemical Pharmacology
影响因子:5.6
doi:10.1016/j.bcp.2016.03.011
Chattopadhyay Debasish, Swingle Mark R, Salter Edward A, Wood Eric, D'Arcy Brandon, Zivanov Catherine, Abney Kevin, Musiyenko Alla, Rusin Scott F, Kettenbach Arminja, Yet Larry, Schroeder Chad E, Golden Jennifer E, Dunham Wade H, Gingras Anne-Claude, Banerjee Surajit, Forbes David, Wierzbicki Andrzej, Honkanen Richard E
免疫/内分泌
发表日期：2016
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Cardioprotection by mild hypothermia during ischemia involves preservation of ERK activity

缺血期间轻度低温的心脏保护作用涉及ERK活性的维持。

期刊:Basic Research in Cardiology
影响因子:8
doi:10.1007/s00395-011-0165-0
Yang, Xiulan; Liu, Yanping; Yang, Xi-Ming; Hu, Fangdi; Cui, Lin; Swingle, Mark R; Honkanen, Richard E; Soltani, Peyman; Tissier, Renaud; Cohen, Michael V; Downey, James M
MAPK/ERK
发表日期：2011
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