日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mutations accumulated in the Spike of SARS-CoV-2 Omicron allow for more efficient counteraction of the restriction factor BST2/Tetherin

SARS-CoV-2 Omicron 刺突蛋白中积累的突变使其能够更有效地对抗限制因子 BST2/Tetherin。

Yuhang Shi ,Sydney Simpson ,Yuexuan Chen ,Haley Aull ,Jared Benjamin ,Ruth Serra-Moreno

The Antiviral Factor SERINC5 Impairs the Expression of Non-Self-DNA

抗病毒因子SERINC5会抑制非自身DNA的表达。

Yuhang Shi ,Sydney Simpson ,Shahad K Ahmed ,Yuexuan Chen ,Aidin Tavakoli-Tameh ,Sanath Kumar Janaka ,David T Evans ,Ruth Serra-Moreno

A cross-stakeholder approach to improving out-of-hospital cardiac arrest survival

采取跨部门合作的方式来提高院外心脏骤停患者的生存率

Guetterman, Timothy C; Forman, Jane; Fouche, Sydney; Simpson, Kaitlyn; Fetters, Michael D; Nelson, Christopher; Mendel, Peter; Hsu, Antony; Flohr, Jessica A; Domeier, Robert; Rahim, Rebal; Nallamothu, Brahmajee K; Abir, Mahshid

Serious Cardiovascular Adverse Events Associated with Hydroxychloroquine/Chloroquine Alone or with Azithromycin in Patients with COVID-19: A Pharmacovigilance Analysis of the FDA Adverse Event Reporting System (FAERS)

COVID-19 患者单独使用羟氯喹/氯喹或与阿奇霉素联合使用时发生的严重心血管不良事件:FDA 不良事件报告系统 (FAERS) 的药物警戒分析

Zhao, Ying; Zhang, Jingru; Zheng, Kai; Thai, Sydney; Simpson, Ross J Jr; Kinlaw, Alan C; Xu, Yang; Wei, Jingkai; Cui, Xiangli; Buse, John B; Stürmer, Til; Wang, Tiansheng

Pharmacokinetics and anti-nausea effects of intravenous ondansetron in hospitalized dogs exhibiting clinical signs of nausea

静脉注射昂丹司琼对出现恶心临床症状的住院犬的药代动力学和止吐作用

Cindy K Sotelo, Sarah B Shropshire, Jessica Quimby, Sydney Simpson, Daniel L Gustafson, Kristin M Zersen

Screening of an FDA-approved compound library identifies levosimendan as a novel anti-HIV-1 agent that inhibits viral transcription

对 FDA 批准的化合物库进行筛选,发现左西孟旦是一种可抑制病毒转录的新型抗 HIV-1 药物

Tsuyoshi Hayashi, Maxime Jean, Huachao Huang, Sydney Simpson, Netty G Santoso, Jian Zhu

Curaxin CBL0100 Blocks HIV-1 Replication and Reactivation through Inhibition of Viral Transcriptional Elongation

Curaxin CBL0100 通过抑制病毒转录延长来阻止 HIV-1 复制和再激活

Maxime J Jean, Tsuyoshi Hayashi, Huachao Huang, Justin Brennan, Sydney Simpson, Andrei Purmal, Katerina Gurova, Michael C Keefer, James J Kobie, Netty G Santoso, Jian Zhu

A Novel Bromodomain Inhibitor Reverses HIV-1 Latency through Specific Binding with BRD4 to Promote Tat and P-TEFb Association

一种新型溴结构域抑制剂通过与 BRD4 特异性结合促进 Tat 和 P-TEFb 结合来逆转 HIV-1 潜伏期

Huachao Huang, Shuai Liu, Maxime Jean, Sydney Simpson, He Huang, Mark Merkley, Tsuyoshi Hayashi, Weili Kong, Irene Rodríguez-Sánchez, Xiaofeng Zhang, Hailemichael O Yosief, Hongyu Miao, Jianwen Que, James J Kobie, James Bradner, Netty G Santoso, Wei Zhang, Jian Zhu

FACT Proteins, SUPT16H and SSRP1, Are Transcriptional Suppressors of HIV-1 and HTLV-1 That Facilitate Viral Latency

FACT 蛋白 SUPT16H 和 SSRP1 是 HIV-1 和 HTLV-1 的转录抑制因子,可促进病毒潜伏期

Huachao Huang, Netty Santoso, Derek Power, Sydney Simpson, Michael Dieringer, Hongyu Miao, Katerina Gurova, Chou-Zen Giam, Stephen J Elledge, Jian Zhu

IFI44 suppresses HIV-1 LTR promoter activity and facilitates its latency

IFI44 抑制 HIV-1 LTR 启动子活性并促进其潜伏期

Derek Power, Netty Santoso, Michael Dieringer, Jack Yu, Huachao Huang, Sydney Simpson, Ishir Seth, Hongyu Miao, Jian Zhu