日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of Orthosteric GABA(B) Receptor Ligands by Virtual Screening and In Vitro Validation.

通过虚拟筛选和体外验证鉴定正构GABA(B)受体配体

Evenseth Linn S M, Russotto Clizia, Wushur Imin, Warszycki Dawid, Moldes-Anaya Angel S, Bojarski Andrzej J, Gabrielsen Mari, Sylte Ingebrigt

Identification of novel N-benzyloxy-amino acid hydroxamates as inhibitors of the virulence factor LasB from Pseudomonas aeruginosa.

鉴定出新型 N-苄氧基氨基酸羟肟酸酯类化合物可作为铜绿假单胞菌毒力因子 LasB 的抑制剂

Di Leo Riccardo, Crispino Enrico, Cuffaro Doretta, Maisetta Giuseppantonio, Bertacca Andrea, Bianchi Marta, Batoni Giovanna, Wushur Imin, Rahman Fatema Amatur, Winberg Jan-Olof, Sylte Ingebrigt, Rossello Armando, Nuti Elisa

Interactions of substrates and phosphinyl containing inhibitors with bacterial and human zinc proteases.

底物和含膦酰基抑制剂与细菌和人类锌蛋白酶的相互作用

Rahman Fatema Amatur, Wushur Imin, Hansen Ida Kristine Østnes, Haug Tor, Stensvåg Klara, Chaulagain Bibek, Nguyen Tra-Mi, Adekoya Olayiwola Adedotun, Malla Nabin, Winberg Jan-Olof, Sylte Ingebrigt

Exploring Conformational Dynamics of the Extracellular Venus flytrap Domain of the GABA(B) Receptor: A Path-Metadynamics Study

探索GABA(B)受体胞外维纳斯捕蝇草结构域的构象动力学:一项路径元动力学研究

Evenseth, Linn S M; Ocello, Riccardo; Gabrielsen, Mari; Masetti, Matteo; Recanatini, Maurizio; Sylte, Ingebrigt; Cavalli, Andrea

The GABA(B) Receptor-Structure, Ligand Binding and Drug Development

GABA(B)受体——结构、配体结合和药物开发

Evenseth, Linn Samira Mari; Gabrielsen, Mari; Sylte, Ingebrigt

In Silico Methods for the Discovery of Orthosteric GABA(B) Receptor Compounds

利用计算机模拟方法发现正构GABA(B)受体化合物

Evenseth, Linn M; Warszycki, Dawid; Bojarski, Andrzej J; Gabrielsen, Mari; Sylte, Ingebrigt

In Silico Site-Directed Mutagenesis Informs Species-Specific Predictions of Chemical Susceptibility Derived From the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) Tool

利用计算机模拟定点诱变技术,结合序列比对预测跨物种化学敏感性(SeqAPASS)工具,可以对物种特异性化学敏感性进行预测。

Doering, Jon A; Lee, Sehan; Kristiansen, Kurt; Evenseth, Linn; Barron, Mace G; Sylte, Ingebrigt; LaLone, Carlie A

Ligand-guided homology modelling of the GABAB2 subunit of the GABAB receptor

配体引导的GABAB受体GABAB2亚基的同源建模

Freyd, Thibaud; Warszycki, Dawid; Mordalski, Stefan; Bojarski, Andrzej J; Sylte, Ingebrigt; Gabrielsen, Mari

Comparative molecular dynamics simulations of mitogen-activated protein kinase-activated protein kinase 5

丝裂原激活蛋白激酶激活蛋白激酶5的比较分子动力学模拟

Lindin, Inger; Wuxiuer, Yimingjiang; Ravna, Aina Westrheim; Moens, Ugo; Sylte, Ingebrigt

Synthesis, antidepressant evaluation and docking studies of long-chain alkylnitroquipazines as serotonin transporter inhibitors

长链烷基硝基喹嗪类化合物作为血清素转运体抑制剂的合成、抗抑郁活性评价及分子对接研究

Gabrielsen, Mari; Wołosewicz, Karol; Zawadzka, Anna; Kossakowski, Jerzy; Nowak, Gabriel; Wolak, Małgorzata; Stachowicz, Katarzyna; Siwek, Agata; Ravna, Aina W; Kufareva, Irina; Kozerski, Lech; Bednarek, Elżbieta; Sitkowski, Jerzy; Bocian, Wojciech; Abagyan, Ruben; Bojarski, Andrzej J; Sylte, Ingebrigt; Chilmonczyk, Zdzisław