CRISPRi screening in cultured human astrocytes uncovers distal enhancers controlling genes dysregulated in Alzheimer's disease
利用 CRISPRi 技术在培养的人类星形胶质细胞中进行筛选，揭示了控制阿尔茨海默病中基因表达失调的远端增强子。
期刊:Nature Neuroscience
影响因子:20
doi:10.1038/s41593-025-02154-3
Green, Nicole F O; Sutton, Gavin J; Pérez-Burillo, Javier; Wang, Juli; Bagot, Samuel; Danon, Hannah G; Walsh, Kieran; Gokool, Akira; Miles, Samantha A; Yang, Guang; Herring, Charles A; Liang, Yuheng; Pfundstein, Grant; Sytnyk, Vladimir; Alinejad-Rokny, Hamid; Lister, Ryan; Rosenbluh, Joseph; Gagnon-Bartsch, Johann A; Voineagu, Irina
