日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Heme-based dioxygenases: Structure, function and dynamics

血红素基双加氧酶:结构、功能和动力学

Geeraerts, Zachary; Ishigami, Izumi; Gao, Yuan; Yeh, Syun-Ru

The Role of Heme Peroxo Oxidants in the Rational Mechanistic Modeling of Nitric Oxide Synthase: Characterization of Key Intermediates and Elucidation of the Mechanism

血红素过氧氧化剂在一氧化氮合酶合理机制建模中的作用:关键中间体的表征和机制的阐明

Mondal, Pritam; Ishigami, Izumi; Yeh, Syun-Ru; Wijeratne, Gayan B

Temperature-dependent structural transition following X-ray-induced metal center reduction in oxidized cytochrome c oxidase

氧化细胞色素c氧化酶中X射线诱导金属中心还原后的温度依赖性结构转变

Ishigami, Izumi; Russi, Silvia; Cohen, Aina; Yeh, Syun-Ru; Rousseau, Denis L

Conformational Plasticity in Human Heme-Based Dioxygenases

人类血红素基双加氧酶的构象可塑性

Khoa N Pham, Ariel Lewis-Ballester, Syun-Ru Yeh

Characterization of the structural determinants of the ubiquitin-dependent proteasomal degradation of human hepatic tryptophan 2,3-dioxygenase

人类肝脏色氨酸 2,3-双加氧酶泛素依赖性蛋白酶体降解的结构决定因素的表征

Yi Liu, Sung-Mi Kim, YongQiang Wang, Shay Karkashon, Ariel Lewis-Ballester, Syun-Ru Yeh, Maria Almira Correia

Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase

二芳基羟胺类化合物可作为吲哚胺2,3-双加氧酶-1、吲哚胺2,3-双加氧酶-2和色氨酸双加氧酶的泛抑制剂或双重抑制剂。

Winters, Maria; DuHadaway, James B; Pham, Khoa N; Lewis-Ballester, Ariel; Badir, Shorouk; Wai, Jenny; Sheikh, Eesha; Yeh, Syun-Ru; Prendergast, George C; Muller, Alexander J; Malachowski, William P

Crystal structure of CO-bound cytochrome c oxidase determined by serial femtosecond X-ray crystallography at room temperature

室温下利用连续飞秒X射线晶体衍射法测定CO结合细胞色素c氧化酶的晶体结构

Ishigami, Izumi; Zatsepin, Nadia A; Hikita, Masahide; Conrad, Chelsie E; Nelson, Garrett; Coe, Jesse D; Basu, Shibom; Grant, Thomas D; Seaberg, Matthew H; Sierra, Raymond G; Hunter, Mark S; Fromme, Petra; Fromme, Raimund; Yeh, Syun-Ru; Rousseau, Denis L

Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (ABC) transporter Rv1747 to regulate mycobacterial growth

结核分枝杆菌通用应激蛋白Rv2623与推定的ATP结合盒(ABC)转运蛋白Rv1747相互作用,从而调节分枝杆菌的生长。

Glass, Lisa N; Swapna, Ganduri; Chavadi, Sivagami Sundaram; Tufariello, JoAnn M; Mi, Kaixia; Drumm, Joshua E; Lam, TuKiet T; Zhu, Guofeng; Zhan, Chenyang; Vilchéze, Catherine; Arcos, Jesus; Chen, Yong; Bi, Lijun; Mehta, Simren; Porcelli, Steven A; Almo, Steve C; Yeh, Syun-Ru; Jacobs, William R Jr; Torrelles, Jordi B; Chan, John

Reaction intermediates in the heme degradation reaction by HutZ from Vibrio cholerae

霍乱弧菌HutZ介导的血红素降解反应中的反应中间体

Uchida, Takeshi; Sekine, Yukari; Dojun, Nobuhiko; Lewis-Ballester, Ariel; Ishigami, Izumi; Matsui, Toshitaka; Yeh, Syun-Ru; Ishimori, Koichiro

Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase

人类色氨酸 2,3-双加氧酶催化和底物介导细胞稳定的分子基础

Ariel Lewis-Ballester, Farhad Forouhar, Sung-Mi Kim, Scott Lew, YongQiang Wang, Shay Karkashon, Jayaraman Seetharaman, Dipanwita Batabyal, Bing-Yu Chiang, Munif Hussain, Maria Almira Correia, Syun-Ru Yeh, Liang Tong