Szabo Roman相关文献与解析，生知库 | 链接生命科学的每一步

Matriptase activation connects tissue factor-dependent coagulation initiation to epithelial proteolysis and signaling

Matriptase 激活将组织因子依赖性凝血启动与上皮蛋白水解和信号传导联系起来

期刊:Blood

影响因子:23.1

doi:10.1182/blood-2015-11-683110

Le Gall, Sylvain M; Szabo, Roman; Lee, Melody; Kirchhofer, Daniel; Craik, Charles S; Bugge, Thomas H; Camerer, Eric

信号转导

发表日期：2016

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TMPRSS13 deficiency impairs stratum corneum formation and epidermal barrier acquisition

TMPRSS13 缺乏会损害角质层形成和表皮屏障的获得。

期刊:Biochemical Journal

影响因子:4.3

doi:10.1042/BJ20140337

Madsen, Daniel H; Szabo, Roman; Molinolo, Alfredo A; Bugge, Thomas H

发表日期：2014

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Membrane-anchored serine proteases in vertebrate cell and developmental biology

脊椎动物细胞和发育生物学中的膜锚定丝氨酸蛋白酶

期刊:Annual Review of Cell and Developmental Biology

影响因子:11.4

doi:10.1146/annurev-cellbio-092910-154247

Szabo, Roman; Bugge, Thomas H

Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice.

HAI2 对细胞表面蛋白酶 matriptase 的调控对于小鼠胎盘发育、神经管闭合和胚胎存活至关重要

期刊:Development

影响因子:3.6

doi:10.1242/dev.038430

Szabo Roman, Hobson John P, Christoph Kristina, Kosa Peter, List Karin, Bugge Thomas H

Matriptase: potent proteolysis on the cell surface

膜蛋白酶：细胞表面强效蛋白水解酶

期刊:Molecular Medicine

影响因子:6.4

doi:10.2119/2006-00022.List

List, Karin; Bugge, Thomas H; Szabo, Roman

细胞生物学

发表日期：2006

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Delineation of matriptase protein expression by enzymatic gene trapping suggests diverging roles in barrier function, hair formation, and squamous cell carcinogenesis

通过酶基因捕获技术对丝氨酸蛋白酶表达的分析表明，其在屏障功能、毛发形成和鳞状细胞癌变中发挥着不同的作用。

期刊:American Journal of Pathology

影响因子:3.6

doi:10.2353/ajpath.2006.051071

List, Karin; Szabo, Roman; Molinolo, Alfredo; Nielsen, Boye Schnack; Bugge, Thomas H

Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation

失调的丝氨酸蛋白酶可导致不依赖于ras的多阶段致癌过程，并促进ras介导的恶性转化。

期刊:Genes & Development

影响因子:7.7

doi:10.1101/gad.1300705

List, Karin; Szabo, Roman; Molinolo, Alfredo; Sriuranpong, Virote; Redeye, Vivien; Murdock, Tricia; Burke, Beth; Nielsen, Boye S; Gutkind, J Silvio; Bugge, Thomas H

Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity.

Matriptase-3 是一种新型的、系统发育上保守的膜锚定丝氨酸蛋白酶，具有广泛的丝氨酸蛋白酶抑制剂反应性

期刊:Biochemical Journal

影响因子:4.3

doi:10.1042/BJ20050299

Szabo Roman, Netzel-Arnett Sarah, Hobson John P, Antalis Toni M, Bugge Thomas H

免疫/内分泌

发表日期：2005

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Membrane-anchored serine proteases as regulators of epithelial function

膜锚定丝氨酸蛋白酶作为上皮功能的调节因子

Matriptase drives early-onset intestinal failure in a mouse model of congenital tufting enteropathy

在先天性簇状肠病的小鼠模型中，Matriptase 可导致早期肠衰竭。

Matriptase activation connects tissue factor-dependent coagulation initiation to epithelial proteolysis and signaling

Matriptase 激活将组织因子依赖性凝血启动与上皮蛋白水解和信号传导联系起来

TMPRSS13 deficiency impairs stratum corneum formation and epidermal barrier acquisition

TMPRSS13 缺乏会损害角质层形成和表皮屏障的获得。

Membrane-anchored serine proteases in vertebrate cell and developmental biology

脊椎动物细胞和发育生物学中的膜锚定丝氨酸蛋白酶

Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice.

HAI2 对细胞表面蛋白酶 matriptase 的调控对于小鼠胎盘发育、神经管闭合和胚胎存活至关重要

Matriptase: potent proteolysis on the cell surface

膜蛋白酶：细胞表面强效蛋白水解酶

Delineation of matriptase protein expression by enzymatic gene trapping suggests diverging roles in barrier function, hair formation, and squamous cell carcinogenesis

通过酶基因捕获技术对丝氨酸蛋白酶表达的分析表明，其在屏障功能、毛发形成和鳞状细胞癌变中发挥着不同的作用。

Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation

失调的丝氨酸蛋白酶可导致不依赖于ras的多阶段致癌过程，并促进ras介导的恶性转化。

Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity.

Matriptase-3 是一种新型的、系统发育上保守的膜锚定丝氨酸蛋白酶，具有广泛的丝氨酸蛋白酶抑制剂反应性