日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Organocatalytic Switches of DNA Glycosylase OGG1 Catalyze a Highly Efficient AP-Lyase Function

DNA糖基化酶OGG1的有机催化开关可催化高效的AP裂解酶功能

Kehler, Mario; Zhou, Kaixin; Kemas, Aurino M; Del Prado, Alicia; Hutchinson, Emma Scaletti; Nairn, Elinor Hesslefors; Varga, Marek; Plattner, Yvonne; Zhong, Yi; Purewal-Sidhu, Oryn; Haslam, James; Wiita, Elisée; Gildie, Heather; Singerova, Karolina; Szaruga, Zuzanna; Almlöf, Ingrid; Hormann, Femke M; Liu, Kang-Cheng; Wallner, Olov; Ortis, Florian; Homan, Evert J; Gileadi, Opher; Rudd, Sean G; Stenmark, Pål; de Vega, Miguel; Helleday, Thomas; D'Arcy-Evans, Nicholas D; Lauschke, Volker M; Michel, Maurice

Integrated stress response activator halofuginone protects mice from diabetes-like phenotypes

综合应激反应激活剂氟吉诺酮保护小鼠免受糖尿病样表型的影响

Shashank Rai, Maria Szaruga, Aleksandra P Pitera, Anne Bertolotti

Activation of the integrated stress response by inhibitors of its kinases

通过激酶抑制剂激活综合应激反应

Maria Szaruga, Dino A Janssen #, Claudia de Miguel #, George Hodgson #, Agnieszka Fatalska, Aleksandra P Pitera, Antonina Andreeva, Anne Bertolotti

Literature Review on Health Emigration in Rare Diseases-A Machine Learning Perspective

罕见病健康移民文献综述——基于机器学习的视角

Skweres-Kuchta, Małgorzata; Czerska, Iwona; Szaruga, Elżbieta

Aβ profiles generated by Alzheimer's disease causing PSEN1 variants determine the pathogenicity of the mutation and predict age at disease onset

阿尔茨海默病引起的 PSEN1 变异产生的 Aβ 谱可确定突变的致病性并预测发病年龄

Dieter Petit #, Sara Gutiérrez Fernández #, Katarzyna Marta Zoltowska, Thomas Enzlein, Natalie S Ryan, Antoinette O'Connor, Maria Szaruga, Elizabeth Hill, Rik Vandenberghe, Nick C Fox, Lucía Chávez-Gutiérrez

Cellular responses to halofuginone reveal a vulnerability of the GCN2 branch of the integrated stress response

细胞对氟吉诺酮的反应揭示了综合应激反应 GCN2 分支的脆弱性

Aleksandra P Pitera, Maria Szaruga, Sew-Yeu Peak-Chew, Steven W Wingett, Anne Bertolotti

Environmental Management from the Point of View of the Energy Intensity of Road Freight Transport and Shocks

从公路货运能源强度和冲击的角度看环境管理

Szaruga, Elżbieta; Załoga, Elżbieta

Spastic paraplegia preceding PSEN1-related familial Alzheimer's disease

痉挛性截瘫先于 PSEN1 相关家族性阿尔茨海默病

Viorica Chelban, Marianthi Breza, Maria Szaruga, Jana Vandrovcova, David Murphy, Chia-Ju Lee, Sondos Alikhwan, Thomas Bourinaris, George Vavougios, Muhammad Ilyas, Sobia Ahsan Halim, Ahmed Al-Harrasi, Chrisoula Kartanou, Coras Ronald, Ingmar Blumcke, Athanasia Alexoudi, Stylianos Gatzonis, Leonidas

Prodromal Alzheimer's Disease: Constitutive Upregulation of Neuroglobin Prevents the Initiation of Alzheimer's Pathology

阿尔茨海默病前驱期:神经球蛋白的组成性上调可阻止阿尔茨海默病理的发生

de Vidania, Silvia; Palomares-Perez, Irene; Frank-García, Ana; Saito, Takashi; Saido, Takaomi C; Draffin, Jonathan; Szaruga, María; Chávez-Gutierrez, Lucía; Calero, Miguel; Medina, Miguel; Guix, Francesc X; Dotti, Carlos G

Qualitative changes in human γ-secretase underlie familial Alzheimer's disease

人类 γ-分泌酶的质变是家族性阿尔茨海默病的根本原因

Maria Szaruga, Sarah Veugelen, Manasi Benurwar, Sam Lismont, Diego Sepulveda-Falla, Alberto Lleo, Natalie S Ryan, Tammaryn Lashley, Nick C Fox, Shigeo Murayama, Harrie Gijsen, Bart De Strooper, Lucía Chávez-Gutiérrez