日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Borrelia burgdorferi serine protease HtrA is a pleiotropic regulator of stress response, motility, flagellar hemostasis, and infectivity

伯氏疏螺旋体丝氨酸蛋白酶HtrA是应激反应、运动性、鞭毛止血和感染性的多效性调节因子。

Zhang, Kai; Sze, Ching Wooen; Zhao, Hang; Liu, Jun; Li, Chunhao

Lactate dehydrogenase is the Achilles' heel of Lyme disease bacterium Borreliella burgdorferi.

乳酸脱氢酶是莱姆病细菌伯氏疏螺旋体的阿喀琉斯之踵

Sze Ching Wooen, Lynch Michael J, Zhang Kai, Neau David B, Ealick Steven E, Crane Brian R, Li Chunhao

The Flagellin-Specific Chaperone FliS of Borrelia burgdorferi Controls the Cytoplasmic Pool of Flagellins at the Level of Translation Initiation, Secretion, and Proteolysis

伯氏疏螺旋体鞭毛蛋白特异性分子伴侣FliS在翻译起始、分泌和蛋白水解水平上调控细胞质鞭毛蛋白库。

Sze, Ching Wooen; Zhang, Kai; Lynch, Michael J; Guo, Wangbiao; Liu, Jun; Crane, Brian R; Li, Chunhao

Lactate dehydrogenase is the Achilles' heel of Lyme disease bacterium Borreliella burgdorferi

乳酸脱氢酶是莱姆病病原体伯氏疏螺旋体的阿喀琉斯之踵。

Sze, Ching Wooen; Lynch, Michael J; Zhang, Kai; Neau, David B; Ealick, Steven E; Crane, Brian R; Li, Chunhao

MCP5, a methyl-accepting chemotaxis protein regulated by both the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, is required for the immune evasion of Borrelia burgdorferi

MCP5是一种甲基受体趋化蛋白,受Hk1-Rrp1和Rrp2-RpoN-RpoS通路调控,是伯氏疏螺旋体逃避免疫所必需的。

Raghunandanan, Sajith; Zhang, Kai; Zhang, Yan; Sze, Ching Wooen; Priya, Raj; Luo, Yongliang; Lynch, Michael J; Crane, Brian R; Li, Chunhao; Yang, X Frank

A chemosensory-like histidine kinase is dispensable for chemotaxis in vitro but regulates the virulence of Borrelia burgdorferi through modulating the stability of RpoS

一种类似化学感受器的组氨酸激酶在体外趋化作用中并非必需,但它通过调节RpoS的稳定性来调控伯氏疏螺旋体的毒力。

Sze, Ching Wooen; Zhang, Kai; Lynch, Michael J; Iyer, Radha; Crane, Brian R; Schwartz, Ira; Li, Chunhao

Chemotaxis Coupling Protein CheW(2) Is Not Required for the Chemotaxis but Contributes to the Full Pathogenicity of Borreliella burgdorferi

趋化性偶联蛋白 CheW(2) 并非趋化作用所必需,但对伯氏疏螺旋体的致病性有贡献。

Sze, Ching Wooen; Li, Chunhao

Viral Membrane Channels: Role and Function in the Virus Life Cycle

病毒膜通道:在病毒生命周期中的作用和功能

Sze, Ching Wooen; Tan, Yee-Joo

NS5B induces up-regulation of the BH3-only protein, BIK, essential for the hepatitis C virus RNA replication and viral release

NS5B诱导BH3结构域蛋白BIK的上调,而BIK对于丙型肝炎病毒RNA复制和病毒释放至关重要。

Aweya, Jude Juventus; Sze, Ching Wooen; Bayega, Anthony; Mohd-Ismail, Nur Khairiah; Deng, Lin; Hotta, Hak; Tan, Yee-Joo

Study of the response regulator Rrp1 reveals its regulatory role in chitobiose utilization and virulence of Borrelia burgdorferi

对反应调节蛋白Rrp1的研究揭示了其在伯氏疏螺旋体几丁质利用和毒力中的调控作用

Sze, Ching Wooen; Smith, Alexis; Choi, Young Hee; Yang, Xiuli; Pal, Utpal; Yu, Aiming; Li, Chunhao