日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A stable, engineered TL1A ligand co-stimulates T cells via specific binding to DR3

稳定的工程化 TL1A 配体通过与 DR3 的特异性结合共刺激 T 细胞

Adam Zwolak #, Szeman Ruby Chan #, Paul Harvilla, Sally Mahady, Anthony A Armstrong, Leopoldo Luistro, Ninkka Tamot, Douglas Yamada, Mehabaw Derebe, Steven Pomerantz, Mark Chiu, Rajkumar Ganesan, Partha Chowdhury

Hyper-Activation of STAT3 Sustains Progression of Non-Papillary Basal-Type Bladder Cancer via FOSL1 Regulome

STAT3 的过度激活通过 FOSL1 调控组维持非乳头状基底型膀胱癌的进展

Luisa Benerini Gatta, Laura Melocchi, Mattia Bugatti, Francesco Missale, Silvia Lonardi, Benedetta Zanetti, Luca Cristinelli, Sandra Belotti, Claudio Simeone, Roberto Ronca, Elisabetta Grillo, Sara Licini, Debora Bresciani, Regina Tardanico, Szeman Ruby Chan, Emanuele Giurisato, Stefano Calza, Willi

Sex as a Biologic Variable in Preclinical Imaging Research: Initial Observations with (18)F-FLT

性别作为临床前影像学研究中的生物学变量:(18)F-FLT 的初步观察

Chan, Szeman Ruby; Salem, Kelley; Jeffery, Justin; Powers, Ginny L; Yan, Yongjun; Shoghi, Kooresh I; Mahajan, Aparna M; Fowler, Amy M

Combination of CD40 Agonism and CSF-1R Blockade Reconditions Tumor-Associated Macrophages and Drives Potent Antitumor Immunity

CD40 激动剂和 CSF-1R 阻断剂的联合作用可重塑肿瘤相关巨噬细胞并产生强大的抗肿瘤免疫力

Karla R Wiehagen, Natasha M Girgis, Douglas H Yamada, Andressa A Smith, Szeman Ruby Chan, Iqbal S Grewal, Michael Quigley, Raluca I Verona

Truncating Prolactin Receptor Mutations Promote Tumor Growth in Murine Estrogen Receptor-Alpha Mammary Carcinomas

截短催乳素受体突变促进小鼠雌激素受体-α乳腺癌中的肿瘤生长

Obi L Griffith, Szeman Ruby Chan, Malachi Griffith, Kilannin Krysiak, Zachary L Skidmore, Jasreet Hundal, Julie A Allen, Cora D Arthur, Daniele Runci, Mattia Bugatti, Alexander P Miceli, Heather Schmidt, Lee Trani, Krishna-Latha Kanchi, Christopher A Miller, David E Larson, Robert S Fulton, William

Novel ERα positive breast cancer model with estrogen independent growth in the bone microenvironment

新型ERα阳性乳腺癌模型,可在骨微环境中实现雌激素非依赖性生长

Capietto, Aude-Hélène; Chan, Szeman Ruby; Ricci, Biancamaria; Allen, Julie A; Su, Xinming; Novack, Deborah V; Schreiber, Robert D; Faccio, Roberta

Longitudinal noninvasive imaging of progesterone receptor as a predictive biomarker of tumor responsiveness to estrogen deprivation therapy

孕激素受体纵向无创成像作为预测肿瘤对雌激素剥夺疗法反应的生物标志物

Chan, Szeman Ruby; Fowler, Amy M; Allen, Julie A; Zhou, Dong; Dence, Carmen S; Sharp, Terry L; Fettig, Nicole M; Dehdashti, Farrokh; Katzenellenbogen, John A

Identifying the initiating events of anti-Listeria responses using mice with conditional loss of IFN-γ receptor subunit 1 (IFNGR1)

使用 IFN-γ 受体亚基 1 (IFNGR1) 条件性缺失的小鼠识别抗李斯特菌反应的起始事件

Sang Hun Lee, Javier A Carrero, Ravindra Uppaluri, J Michael White, Jessica M Archambault, Koon Siew Lai, Szeman Ruby Chan, Kathleen C F Sheehan, Emil R Unanue, Robert D Schreiber

STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas

STAT1 缺陷小鼠自发发展雌激素受体 α 阳性乳腺腔内癌

Szeman Ruby Chan, William Vermi, Jingqin Luo, Laura Lucini, Charles Rickert, Amy M Fowler, Silvia Lonardi, Cora Arthur, Larry Jt Young, David E Levy, Michael J Welch, Robert D Cardiff, Robert D Schreiber

Small-animal PET of steroid hormone receptors predicts tumor response to endocrine therapy using a preclinical model of breast cancer

利用乳腺癌临床前模型,通过小动物PET成像检测类固醇激素受体,预测肿瘤对内分泌治疗的反应

Fowler, Amy M; Chan, Szeman Ruby; Sharp, Terry L; Fettig, Nicole M; Zhou, Dong; Dence, Carmen S; Carlson, Kathryn E; Jeyakumar, M; Katzenellenbogen, John A; Schreiber, Robert D; Welch, Michael J