日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A phospho-dawn of protein modification anticipates light onset in the picoeukaryote Ostreococcus tauri

蛋白质修饰的磷酸化曙光预示着微微真核生物Ostreococcus tauri的光照开始

Zeenat B Noordally, Matthew M Hindle, Sarah F Martin, Daniel D Seaton, T Ian Simpson, Thierry Le Bihan, Andrew J Millar

Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism

神经元和神经元活动控制星形胶质细胞中的基因表达,以调节其发育和代谢

Philip Hasel, Owen Dando, Zoeb Jiwaji, Paul Baxter, Alison C Todd, Samuel Heron, Nóra M Márkus, Jamie McQueen, David W Hampton, Megan Torvell, Sachin S Tiwari, Sean McKay, Abel Eraso-Pichot, Antonio Zorzano, Roser Masgrau, Elena Galea, Siddharthan Chandran, David J A Wyllie, T Ian Simpson, Giles E H

Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons

发育神经元中活动依赖性基因表达进化分化的证据

Jing Qiu, Jamie McQueen, Bilada Bilican, Owen Dando, Dario Magnani, Karolina Punovuori, Bhuvaneish T Selvaraj, Matthew Livesey, Ghazal Haghi, Samuel Heron, Karen Burr, Rickie Patani, Rinku Rajan, Olivia Sheppard, Peter C Kind, T Ian Simpson, Victor Lj Tybulewicz, David Ja Wyllie, Elizabeth Mc Fisher

Analysis of compound heterozygotes reveals that the mouse floxed Pax6 (tm1Ued) allele produces abnormal eye phenotypes

复合杂合子的分析表明,小鼠 floxed Pax6 (tm1Ued) 等位基因产生异常的眼睛表型

Natalie J Dorà, Aaron J F Crookshanks, Karen K Y Leung, T Ian Simpson, John O Mason, David J Price, John D West

Network analyses reveal novel aspects of ALS pathogenesis

网络分析揭示了 ALS 发病机制的新方面

Mario Sanhueza, Andrea Chai, Colin Smith, Brett A McCray, T Ian Simpson, J Paul Taylor, Giuseppa Pennetta

NMDA receptor-dependent regulation of miRNA expression and association with Argonaute during LTP in vivo

体内 LTP 期间 NMDA 受体依赖性 miRNA 表达调节及其与 Argonaute 的关联

Balagopal Pai, Taweeporn Siripornmongcolchai, Birgitte Berentsen, Ashraf Pakzad, Christel Vieuille, Ståle Pallesen, Maciej Pajak, T Ian Simpson, J Douglas Armstrong, Karin Wibrand, Clive R Bramham

Pax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRb

Pax6 通过直接抑制 Cdk6 和 pRb 的低磷酸化对皮质祖细胞增殖进行区域控制

Da Mi, Catherine B Carr, Petrina A Georgala, Yu-Ting Huang, Martine N Manuel, Emily Jeanes, Emi Niisato, Stephen N Sansom, Frederick J Livesey, Thomas Theil, Kerstin Hasenpusch-Theil, T Ian Simpson, John O Mason, David J Price

Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization

体内控制 Pax6 的过度表达会对 Pax6 基因座进行负向自我调节,导致晚期皮质祖细胞增殖的细胞自主缺陷,而对皮质区域化影响不大

Martine Manuel, Petrina A Georgala, Catherine B Carr, Simon Chanas, Dirk A Kleinjan, Ben Martynoga, John O Mason, Michael Molinek, Jeni Pinson, Thomas Pratt, Jane C Quinn, T Ian Simpson, David A Tyas, Veronica van Heyningen, John D West, David J Price

The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse

翼螺旋转录因子 Foxg1 促进小鼠视网膜神经节细胞轴突跨越腹侧中线

Thomas Pratt, Natasha M M-L Tian, T Ian Simpson, John O Mason, David J Price