PIK3CA mutations can initiate pancreatic tumorigenesis and are targetable with PI3K inhibitors
PIK3CA突变可启动胰腺肿瘤发生,并可通过PI3K抑制剂进行靶向治疗。
期刊:Oncogenesis
影响因子:5.9
doi:10.1038/oncsis.2015.28
S N Payne ,M E Maher ,N H Tran ,D R Van De Hey ,T M Foley ,A E Yueh ,A A Leystra ,C A Pasch ,J J Jeffrey ,L Clipson ,K A Matkowskyj ,D A Deming