Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring (V600E)BRAF
PTEN 和 RB1 肿瘤抑制基因同时缺失可减弱携带 (V600E)BRAF 的黑色素瘤对 RAF 的依赖性
期刊:Oncogene
影响因子:6.9
doi:10.1038/onc.2011.250
F Xing, Y Persaud, C A Pratilas, B S Taylor, M Janakiraman, Q-B She, H Gallardo, C Liu, T Merghoub, B Hefter, I Dolgalev, A Viale, A Heguy, E De Stanchina, D Cobrinik, G Bollag, J Wolchok, A Houghton, D B Solit